Now showing items 1-12 of 12

  • Aerobic interval exercise improves parameters of nonalcoholic fatty liver disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. 

    Kapravelou, Garyfallia; Martinez, Rosario; Andrade, Ana M.; Nebot, Elena; Camiletti-Moiron, Daniel; Aparicio, Virginia A.; Lopez-Jurado, Maria; Aranda, Pilar; Arrebola, Francisco; Fernandez-Segura, Eduardo; Bermano, Giovanna; Goua, Marie; Galisteo, Milagros; Porres, Jesus M. (NRC Research Press https://dx.doi.org/10.1139/apnm-2015-0141, 2015-08-14)
    KAPRAVELOU, G., MARTINEZ, R., ANDRADE, A.M., NEBOT, E., CAMILETTI-MOIRON, D., APARICIO, V.A., LOPEZ-JURADO, M., ARANDA, P., ARREBOLA, F., FERNANDEZ-SEGURA, E., BERMANO, G., GOUA, M., GALISTEO, M. and PORRES, J.M. 2015. Aerobic interval exercise improves parameters of non-alcoholic fatty liver disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. Applied physiology, nutrition, and metabolism [online], 40(12), pages 1242-1252. Available from: https://dx.doi.org/10.1139/apnm-2015-0141
    Metabolic syndrome (MS) is a group of metabolic alterations that increase the susceptibility to cardiovascular disease and type 2 diabetes. Nonalcoholic fatty liver disease has been described as the liver manifestation of ...
  • Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. 

    Barron, Gemma A.; Goua, Marie; Kuraoka, Isao; Bermano, Giovanna; Iwai, Shigenori; Lin, Paul Kong Thoo (Elsevier http://dx.doi.org/10.1016/j.cbi.2015.10.017, 2015-12-05)
    BARRON, G. A., GOUA, M., KURAOKA, I., BERMANO, G., IWAI, S. and LIN, P. K. T. L., 2015. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions, Vol 242, pp. 307-315.
    Bisnaphthalimidopropyl diaminodicyclohexylmethane (BNIPDaCHM) bisintercalates to DNA and is a potential anti-cancer therapeutic. In an attempt to elucidate the mechanism(s) underlying the potential of BNIPDaCHM; earlier ...
  • Can selenium supplementation modify oxidative stress in-vitro? A role for selenium supplementation in the prevention of cardiovascular disease. 

    Leighton, Dean; Goua, Marie; Dolan, Eimear; Burgess, Katherine; Bermano, Giovanna (BioMed Central http://www.journal-inflammation.com/content/12/S1/P7, 2015-04)
    LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G., 2015. Can selenium supplementation modify oxidative stress in-vitro? A role for selenium supplementation in the prevention of cardiovascular disease. Journal of Inflammation, 12 (Suppl. 1), p.7.
    Two thirds of the UK population are either overweight or obese (body mass index (BMI) 25-29.9 and >30 kg/m2 respectively) and are typically characterised by systemic oxidative stress (OS); deemed to play a key role in ...
  • Competencies and skills to enable effective care of severely obese patients undergoing bariatric surgery across a multi-disciplinary healthcare perspective: a systematic review. 

    Stephen, Audrey I.; Bermano, Giovanna; Bruce, Duff; Kirkpatrick, Pamela (The Joanna Briggs Institute, University of Adelaide. http://dx.doi.org/10.11124/jbisrir-2014-1583, 2014-09)
    STEPHEN, A., BERMANO, G., BRUCE, D. and KIRKPATRICK, P., 2014. Competencies and skills to enable effective care of severely obese patients undergoing bariatric surgery across a multi-disciplinary healthcare perspective: a systematic review. JBI Database of Systematic Reviews and Implementation Reports, 12 (9), pp. 321-397.
    Executive summary Background The incidence of severe and complex obesity with co-morbidity and high risk of mortality is increasing globally. Bariatric surgery is the only intervention leading to sustained weight reduction, ...
  • Control of surface interactions with ultra-violet/ozone modification at polystyrene surface. 

    Liang, He (Robert Gordon University School of Engineering, 2014-01)
    Surface interactions and reactivity are of critical importance in current biomedical technologies, for example, satisfactory cell attachment and long term viability are essential for optimal in vitro tissue culture and for ...
  • Impact of high intensity interval training (HIIT) and/or selenium (Se) supplementation on oxidative stress and antioxidant status in active females. 

    Keane, Karen (Robert Gordon University Centre for Obesity Research and Epidemiology, 2014-02)
    Background: Cells continuously produce free radicals (FR) and reactive oxygen species (ROS) as part of metabolic processes. These free radicals are neutralized by an elaborate antioxidant defence system consisting of ...
  • Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. 

    Weichhaus, Michael; Broom, John; Wahle, Klaus; Bermano, Giovanna (Spandidos Publications. http://dx.doi.org/10.3892/ol.2014.2085, 2014-07)
    WEICHHAUS, M., BROOM, J., WAHLE, K. and BERMANO, G., 2014. Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. Oncology Letters, 8 (1), pp. 374-378.
    Leptin is a hormone secreted by white fat tissue and signals the amount of overall body fat to the hypothalamus. The circulating concentration of leptin correlates with the level of obesity. Breast cancer risk is higher ...
  • Molecular aspects of the link between obesity, insulin resistance and breast cancer. 

    Weichhaus, Michael (The Robert Gordon University Centre for Obesity Research and Epidemiology (CORE), 2010-11)
    WEICHHAUS, M., BROOM, I. and BERMANO, G., 2010. The molecular contribution of TNF-alpha in the link between obesity and breast cancer. Oncology Reports (in press)
     
    WEICHHAUS, M., BROOM, I., WAHLE, K. and BERMANO, G., 2009. Insulin-induced gene expression changes in breast cancer cells and normal breast epithelial cells. Poster presented at 17th European Congress in Obesity (ECO) in Amsterdam. Obesity Facts, 2 (Suppl. 2 ), p. S172
     
    WEICHHAUS, M., BROOM, I., WAHLE, K. and BERMANO, G., 2008. Molecular aspects linking insulin resistance to breast cancer by activation of cell signalling pathways. Poster presented at 6th Annual World Congress on the Insulin Resistance Syndrome (WCIRS) in Los Angeles. Diabetes and Vascular Disease Research, 5 (3), P. 233
     
    WEICHHAUS, M., BROOM, I., WAHLE, K. and BERMANO, G., 2008. Molecular aspects of insulin resistance, cell signalling pathways and breast cancer in relation to obesity. Poster presented at the 16th European Congress on Obesity (ECO2008) in Geneva. International Journal of Obesity, 32 (Suppl. 1), P. S38
     
    WEICHHAUS, M., BROOM, I., WAHLE, K. and BERMANO, G., 2009. Effect of hypeinsulinaemia and impaired adipokines secretion on proliferation of human breast cancer and normal human breast epithelial cells. Oral presentation at the 5th Asia-Oceania Conference on Obesity (AOCO) in Mumbai. International Journal of Diabetes in Developing Countries, 28, P. S21
     
    Obesity is a multi-factorial metabolic disease, resulting in increased adipose tissue acquisition by the host. This disease increases the risk for developing co-morbidities, including Metabolic Syndrome and other disorders ...
  • Novel bisnaphthalimidopropyl polyamine derivatives: their mode of action in a breast cancer cell system. 

    Barron, Gemma A. (The Robert Gordon University School of Pharmacy and Life Sciences, 2010-06)
    BARRON, G. A., BERMANO, G., GORDON, A. and LIN, Paul K. T., 2010. Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells. European Journal of Medicinal Chemistry, 45, pp. 1430-1437.
     
    BARRON, G., BERMANO, G., GORDON, A., RALTON, L. and KONG, T. L. P., 2006. The in vitro studies of novel Bis-naphthalimidopropyl polyamine derivatives against CaCO-2 cells. Poster presentation at Health Implications of Dietary Amines - a Joint COST Action 922 and Biochemical Society Focused Meeting (Biochemistry Society meeting), Aberdeen, UK, 19-21 October 2006.
     
    BARRON, G., BERMANO, G., GORDON, A. and LIN, P. K. T., 2008. Synthesis, cytotoxicity and DNA binding studies of novel Bisnaphthalimidopropyl polyamine derivatives (BNIPPs). Poster presentation at Industry Tours for Postgraduates (Royal Society of Chemistry), Edinburgh/Glasgow, UK, 16-18 March 2008 and 9th Tetrahedron Symposium challenges in Organic and Bioorganic Chemistry (Elsevier meeting), Berkeley, USA, 22-25 July 2008.
     
    The synthesis and characterisation of novel bisnaphthalimidopropyl polyamine (BNIPP) derivatives, has gained pace over the last couple of years, as they have enhanced aqueous solubility, without loss of biological activity, ...
  • Obesity and its health impact in Africa: a systematic review. 

    Adeboye, Bridget; Bermano, Giovanna; Rolland, Catherine (Clinics Cardive Publishing. http://dx.doi.org/10.5830/CVJA-2012-040, 2012-10)
    ADEBOYE, B., BERMANO, G. and ROLLAND, C., 2012. Obesity and its health impact in Africa: a systematic review. Cardiovascular Journal of Africa, 23 (9), pp. 512-521.
    Obesity and its association with co-morbidities in Africa are on the rise. This systematic review examines evidence of obesity and its association with co-morbidities within the African continent. Comparative studies ...
  • Selenoprotein expression in the rat colon during Se deficiency. 

    Pagmantidis, V.; Bermano, Giovanna; Broom, John; Arthur, J. R.; Hesketh, J. E. (Cambridge University Press. http://dx.doi.org/10.1017/S0029665102000228, 2002-05)
    PAGMANTIDIS, V., BERMANO, G., BROOM, J., ARTHUR, J. R. and HESKETH, J. E., 2002. Selenoprotein expression in the rat colon during Se deficiency. Proceedings of the Nutrition Society, 61 (2A), 51A
  • Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. 

    Pagmantidis, V.; Villette, S.; Bermano, Giovanna; Broom, John; Arthur, J. R.; Hesketh, J. E. (Cambridge University Press. http://dx.doi.org/10.1079/PNS2003XXX, 2003-09)
    PAGMANTIDIS, V., VILLETTE, S., BERMANO, G., BROOM, J., ARTHUR, J. R. and HESKETH, J. E., 2003. Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. Proceedings of the Nutrition Society, 62 (1A), 72A