Now showing items 9-18 of 18

  • Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. 

    Weichhaus, Michael; Broom, John; Wahle, Klaus; Bermano, Giovanna (Spandidos Publications. http://dx.doi.org/10.3892/ol.2014.2085, 2014-07)
    WEICHHAUS, M., BROOM, J., WAHLE, K. and BERMANO, G., 2014. Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. Oncology Letters, 8 (1), pp. 374-378.
    Leptin is a hormone secreted by white fat tissue and signals the amount of overall body fat to the hypothalamus. The circulating concentration of leptin correlates with the level of obesity. Breast cancer risk is higher ...
  • Molecular aspects of the link between obesity, insulin resistance and breast cancer. 

    Weichhaus, Michael (The Robert Gordon University Centre for Obesity Research and Epidemiology (CORE), 2010-11)
    Obesity is a multi-factorial metabolic disease, resulting in increased adipose tissue acquisition by the host. This disease increases the risk for developing co-morbidities, including Metabolic Syndrome and other disorders ...
  • Over-the-counter Orlistat: early experiences, views and attitudes of community pharmacists in Great Britain. 

    Weidmann, Anita Elaine; Cunningham, Scott; Gray, Gwen; Hansford, Denise; McLay, James S.; Broom, John; Stewart, Derek C. (Springer Verlag http://dx.doi.org/10.1007/s11096-011-9516-z, 2011-08)
    WEIDMAN, A. E., CUNNINGHAM, S., GRAY, G., HANSFORD, D., MCLAY, J., BROOM, J. and STEWART, D., 2011. Over-the-counter Orlistat: early experiences, views and attitudes of community pharmacists in Great Britain. International Journal of Clinical Pharmacy, 33 (4), pp. 627-633.
    Objectives of the study To describe community pharmacists’ early experiences, views and attitudes with over-the-counter orlistat, 9 months post legal re-classification from November 2009 to January 2010. Setting 13,200 ...
  • Selenoprotein expression in the rat colon during Se deficiency. 

    Pagmantidis, V.; Bermano, Giovanna; Broom, John; Arthur, J. R.; Hesketh, J. E. (Cambridge University Press. http://dx.doi.org/10.1017/S0029665102000228, 2002-05)
    PAGMANTIDIS, V., BERMANO, G., BROOM, J., ARTHUR, J. R. and HESKETH, J. E., 2002. Selenoprotein expression in the rat colon during Se deficiency. Proceedings of the Nutrition Society, 61 (2A), 51A
  • Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. 

    Pagmantidis, V.; Villette, S.; Bermano, Giovanna; Broom, John; Arthur, J. R.; Hesketh, J. E. (Cambridge University Press. http://dx.doi.org/10.1079/PNS2003XXX, 2003-09)
    PAGMANTIDIS, V., VILLETTE, S., BERMANO, G., BROOM, J., ARTHUR, J. R. and HESKETH, J. E., 2003. Selenoprotein gene expression in an intestinal cell line during selenium depletion: a macroarray approach indicates effects on SelW and glutathione peroxidise 1. Proceedings of the Nutrition Society, 62 (1A), 72A
  • Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. 

    Heys, S. D.; Park, K. G. M.; McNurlan, M. A.; Milne, E.; Keenan, R. A.; Miller, J. D. B.; Broom, John; Eremin, O.; Garlick, P. J. (Cambridge University Press http://dx.doi.org/10.1079/PNS19900038, 1990-07)
    HEYS, S. D., PARK, K. G. M., McNURLAN, M. A., MILNE, E., KEENAN, R. A., MILLER, J. D. B., BROOM, J., EREMIN, O. and GARLICK, P. J., 1990. Stimulation of colorectal tumour protein synthesis, in vivo, by nutritional support. Proceedings of the Nutrition Society, 49 (2), 165A
  • A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. 

    Hepburn, D.; Broom, John; Smith, D. J. (Cambridge University Press. http://dx.doi.org/10.1079/PNS19860044, 1986-02)
    HEPBURN, D., BROOM, J. and SMITH, D. J., 1986. A study of the time course of fructose-2, 6-bisphosphate production in a septic mouse model. Proceedings of the Nutrition Society, 45 (1), 33A.
  • Systematic review of exercise and the long-term outcomes of the treatment for obesity. 

    Brown, T. J.; Avenell, A.; Broom, John; Smith, W. C. S.; Jung, R.; Campbell, M. K.; Grant, A. M. (Cambridge University Press. http://dx.doi.org/10.1017/S0029665102000289, 2002-11)
    BROWN, T. J., AVENELL, A., BROOM, J., SMITH, W. C. S., JUNG, R., CAMPBELL, M. K. and GRANT, A. M., 2002. Systematic review of exercise and the long-term outcomes of the treatment for obesity. Proceedings of the Nutrition Society, 61 (3A), 154A.
  • Very-low-energy diets and morbidity: a systematic review of longer-term evidence. 

    Mulholland, Yvonne; Nicokavoura, Efsevia; Broom, John; Rolland, Catherine (Cambridge University Press http://dx.doi.org/10.1017/S0007114512001924, 2012-09)
    MULHOLLAND, Y., NICOKAVOURA, E., BROOM, J. and ROLLAND, C., 2012. Very-low-energy diets and morbidity: a systematic review of longer-term evidence. British Journal of Nutrition, 108 (5), pp. 832-851.
    Evidence from the literature supports the safe use of very-low-energy diets (VLED) for up to 3 months in supervised conditions for patients who fail to meet a target weight loss using a standard low-fat, reduced-energy ...
  • Weight loss for women with and without polycystic ovary syndrome following a very low-calorie diet in a community-based setting with trained facilitators for 12 weeks. 

    Nikokavoura, Efsevia Anastasia; Johnston, Kelly L.; Broom, John; Wrieden, Wendy L.; Rolland, Catherine (Dove Medical Press http://dx.doi.org/10.2147/DMSO.S85134, 2015-10)
    NIKOKAVOURA, E. A., JOHNSTON, E. L., BROOM, J., WRIEDEN, W. L. and ROLLAND, C., 2015. Weight loss for women with and without polycystic ovary syndrome following a very low-calorie diet in a community-based setting with trained facilitators for 12 weeks. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2015:8, pp. 495-503.
    Background: Polycystic ovary syndrome (PCOS) affects between 2% and 26% of reproductive-age women in the UK, and accounts for up to 75% of anovulatory infertility. The major symptoms include ovarian disruption, hyperandrogenism, ...