Now showing items 1-5 of 5

  • The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis. 

    Bahmed, Amina (Robert Gordon University School of Pharmacy and Life Sciences, 2015-05)
    Cystinosis is a metabolic disorder characterised by the abnormal accumulation of the amino acid cystine in cells leading to a slow destruction of all major organs. If patients diagnosed with cystinosis are untreated, death ...
  • Development of novel nutrapharmaceuticals combining the anti-oxidant and anti-inflammatory properties of n-3 fatty acids with a nitric oxide donor - a potential new preventative strategy for heart disease. 

    Rowell, Owen (Robert Gordon University School of Pharmacy and Life Sciences, 2011-11)
    Atherosclerosis is a cardiovascular disease which forms plaques which narrow the arteries, restricting blood flow and thus increasing blood pressure. As this can lead to more serious conditions, such as myocardial infarction, ...
  • Formulation studies on cysteamine for the treatment of nephropathic cystinosis. 

    Buchan, Barbara Elizabeth (Robert Gordon University School of Pharmacy and Life Sciences, 2011-08)
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of almost all organs. It is treated by regular oral and topical administration of the aminothiol, ...
  • Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. 

    McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H.; Knott, Rachel M.; Cairns, Donald (Elsevier https://doi.org/10.1016/j.ijpharm.2016.10.044, 2016-10-19)
    MCKENZIE, B., KAY, G., MATTHEWS, K.H., KNOTT, R. and CAIRNS, D. 2016. Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. International journal of pharmaceutics [online], 515(1-2), pages 575-582. Available from: https://doi.org/10.1016/j.ijpharm.2016.10.044
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of all organs. It is treated by regular administration of the aminothiol, cysteamine. Corneal ...
  • Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. 

    Benylles, Amina; Cairns, Donald; Cox, Philip J.; Kay, Graeme (International Union of Crystallography. http://dx.doi.org/10.1107/S0108270113012377, 2013-06)
    BENYLLES, A., CAIRNS, D., COX, P. J. and KAY, G., 2013. Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. Acta Crystallographica Section C: Crystal Structure Communications, C69, 658-664.
    Reaction between cyste­amine (systematic name: 2-amino­ethane­thiol, C2H7NS) and L-(+)-tartaric acid [systematic name: (2R,3R)-2,3-di­hydroxy­butane­dioic acid, C4H6O6] results in a mixture of cyste­amine tartrate(1-) ...