Now showing items 4-6 of 6

  • Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. 

    McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H.; Knott, Rachel M.; Cairns, Donald (Elsevier https://doi.org/10.1016/j.ijpharm.2016.10.044, 2016-10-19)
    MCKENZIE, B., KAY, G., MATTHEWS, K.H., KNOTT, R. and CAIRNS, D. 2016. Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. International journal of pharmaceutics [online], 515(1-2), pages 575-582. Available from: https://doi.org/10.1016/j.ijpharm.2016.10.044
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of all organs. It is treated by regular administration of the aminothiol, cysteamine. Corneal ...
  • Suppository formulations as a potential treatment for nephropathic cystinosis. 

    McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H.; Cairns, Donald (Elsevier https://doi.org/10.1002/jps.23246, 2012-07-06)
    BUCHAN, B., KAY, G., MATTHEWS, K.H. and CAIRNS, D. 2012. Suppository formulations as a potential treatment for nephropathic cystinosis. Journal of pharmaceutical sciences [online], 101(10), pages 3729-2738. Available from: https://doi.org/10.1002/jps.23246
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of all the organs. It is treated by the 6-h oral administration of the aminothiol, cysteamine, ...
  • Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. 

    Benylles, Amina; Cairns, Donald; Cox, Philip J.; Kay, Graeme (International Union of Crystallography. http://dx.doi.org/10.1107/S0108270113012377, 2013-06)
    BENYLLES, A., CAIRNS, D., COX, P. J. and KAY, G., 2013. Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. Acta Crystallographica Section C: Crystal Structure Communications, C69, 658-664.
    Reaction between cyste­amine (systematic name: 2-amino­ethane­thiol, C2H7NS) and L-(+)-tartaric acid [systematic name: (2R,3R)-2,3-di­hydroxy­butane­dioic acid, C4H6O6] results in a mixture of cyste­amine tartrate(1-) ...