Now showing items 10-12 of 12

  • Studies on the role of the endocannabinoid anandamide, as a possible modulator of events during neointimal formation. 

    Skene, Karen E. (The Robert Gordon University School of Pharmacy and Life Sciences., 2010-04)
    Neointimal formation is a complex process that occurs due to the over compensatory healing response produced by the vessel following injury. Three key events, SMC proliferation, SMC migration and the inflammatory response, ...
  • Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. 

    Ibie, Chidinma O.; Thompson, Colin J.; Knott, Rachel M. (Springer https://doi.org/10.1007/s00396-015-3561-4, 2015-03-24)
    IBIE, C.O., THOMPSON, C.J. and KNOTT, R. 2015. Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. Colloid and polymer science [online], 293(6), pages 1737-1748. Available from: https://doi.org/10.1007/s00396-015-3561-4
    Polyallylamine (Paa) was quaternised by methylation of its primary amines using methyl iodide to yield quaternised Paa (QPaa). Average level of polymer quaternisation was determined by elemental analysis and was found to ...
  • Use of a three dimensional porcine retinal explant model to detect HIF1 alpha for understanding diabetic retinopathy. 

    Iwuagwu, Benedicta; Cruickshank, Stuart F.; Rowe, Iain; Knott, Rachel M. (ASBMB https://www.asbmb.org/meeting2017/, 2017-04-22)
    IWUAGWU, B.U., CRUICKSHANK, S.F., ROWE, I. and KNOTT, R.M. 2017. Use of a three dimensional porcine retinal explant model to detect HIF1 alpha for understanding diabetic retinopathy. Presented at the American Society for Biochemistry and Molecular Biology annual meeting (ASBMB 2017), 22-26 April 2017, Chicaco, USA.
    Diabeticretinopathy (DR) is a major microvascular complication associated with diabetes mellitus and is a leading cause of blindness. Hypoxia and hyperglycemia are suggested to play crucial pathophysiological roles, but ...