Now showing items 3-9 of 9

  • Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. 

    Medu, Erere Ohwofasa (Robert Gordon University School of Pharmacy and Life Sciences, 2013-05)
    In view of the increasing global challenge of bacterial resistance, there exists an urgent need for the rationale development of antibacterial compounds with either novel or multiple mechanisms of action. Two chalcone-derivatives, ...
  • Formulation studies on cysteamine for the treatment of nephropathic cystinosis. 

    Buchan, Barbara Elizabeth (Robert Gordon University School of Pharmacy and Life Sciences, 2011-08)
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of almost all organs. It is treated by regular oral and topical administration of the aminothiol, ...
  • Investigation into the antimicrobial activity of cationic antibacterials. 

    O'Driscoll, Noelle H. (Robert Gordon University School of Pharmacy and Life Sciences, 2011-08)
    The topic addressed by the 2011 WHO‘s World Health Day was antibacterial resistance. This action served to highlight the serious problem bacterial resistance now presents to healthcare professionals globally. This investigation ...
  • The molecular mechanisms of diabetes mediated impaired wound healing and the development of therapeutic strategies. 

    Gadad, Pramod C. (The Robert Gordon University School of Pharmacy and Life Sciences, 2011-01)
    Increased levels of blood glucose are associated with the vascular complications of diabetes. Microvascular complications lead to delayed wound healing in patients suffering from diabetes. Hypoxia and hyperglycaemia ...
  • A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate. 

    Sartawi, Ziad (Robert Gordon University School of Pharmacy and Life Sciences, 2015-06)
    Polyelectrolytes are charge carrying polymers, when two oppositely charged polyelectrolytes are combined in a solution favouring charge expression, a polyelectrolyte complex can result. These complexes have been shown to ...
  • Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. 

    McKenzie, Barbara; Kay, Graeme; Matthews, Kerr H.; Knott, Rachel M.; Cairns, Donald (Elsevier https://doi.org/10.1016/j.ijpharm.2016.10.044, 2016-10-19)
    MCKENZIE, B., KAY, G., MATTHEWS, K.H., KNOTT, R. and CAIRNS, D. 2016. Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis. International journal of pharmaceutics [online], 515(1-2), pages 575-582. Available from: https://doi.org/10.1016/j.ijpharm.2016.10.044
    Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of all organs. It is treated by regular administration of the aminothiol, cysteamine. Corneal ...
  • A preliminary investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry. 

    Bibi, Shahdia; Bremner, D. H.; Macdougall-Heasman, M.; Reid, R.; Simpson, K.; Tough, Ann; Waddell, Stuart; Stewart, I. J.; Matthews, Kerr H. (Royal Society of Chemistry http://dx.doi.org/10.1039/C5AY01711D, 2015-10)
    BIBI, S., BREMNER, D. H., MACDOUGALL-HEASMAN, M., REID, R., SIMPSON, K., TOUGH, A., WADDELL, S., STEWART, I. J. and MATTHEWS, K. H., 2015. A preliminary investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry. Analytical Methods, 2015, 7, pp. 8597-8604.
    Increasing numbers of illicit and unlicensed medicines are in general circulation and regularly seized by the police and other regulatory authorities. Forensic identification of seized tablets tends to focus on ...