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  • Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. 

    Bestwick, Charles S.; Milne, Lesley; Dance, Anne-Marie; Cochennec, Gaela; Cruickshank, Gillian; Allain, Eflamm; Constable, Lynda; Duthie, Susan J.; Kong Thoo Lin, Paul (Elsevier https://doi.org/10.1016/j.tiv.2018.06.023, 2018-07-23)
    BESTWICK, C., MILNE, L., DANCE, A.-M., COCHENNEC, G., CRUICKSHANK, G., ALLAIN, E., CONSTABLE, L., DUTHIE, S. and KONG THOO LIN, P. 2018. Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. Toxicology in vitro [online], 52, pages 342-350. Available from: https://doi.org/10.1016/j.tiv.2018.06.023
    Bisnaphthalimides are DNA intercalators of potential use as chemotherapeutics but for which the range of mechanism of action is only gradually being elucidated. Using human promyelocytic HL-60 cells, we extend characterization ...