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  • GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues. 

    Lipina, Christopher; Walsh, Sarah K.; Mitchell, Sharon E.; Speakman, John R.; Wainwright, Cherry L.; Hundal, Harinder S. (FASEB (Federation of American Society of Experimental Biology) https://doi.org/10.1096/fj.201800171R, 2018-08-27)
    LIPINA, C., WALSH, S.K., MITCHELL, S.E., SPEAKMAN, J.R., WAINWRIGHT, C.L. and HUNDAL, H.S. 2018. GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues. The FASEB journal [online], Early Online. Available from: https://doi.org/10.1096/fj.201800171R
    Emerging evidence indicates that G-protein coupled receptor 55 (GPR55), a nonclassic receptor of the endocannabinoid system that is activated by L-α-lysophosphatidylinositol and various cannabinoid ligands, may regulate ...
  • l‐α‐Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK‐dependent pathway. 

    Robertson-Gray, Olivia Jane; Walsh, Sarah K.; Ryberg, Erik; Jönsson‐Rylander, Ann‐Cathrine; Lipina, Christopher; Wainwright, Cherry L. (Wiley https://doi.org/10.1002/prp2.487, 2019-05-24)
    ROBERTSON-GRAY, O.J., WALSH, S.K., RYBERG, E., JÖNSSON-RYLANDER, A.-C., LIPINA, C. and WAINWRIGHT, C.L. 2019. l‐α‐Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK‐dependent pathway. Pharmacology research and perspectives [online], 7(3), article ID e00487. Available from: https://doi.org/10.1002/prp2.487
    The phospholipid l-α-lysophosphatidylinositol (LPI), an endogenous ligand for GPR55, is elevated in patients with acute coronary syndrome, and a GPR55 antagonist cannabidiol (CBD) reduces experimental ischemia/reperfusion ...