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  • Interactions of platinum compounds with heterocyclic bases. 

    Taylor, Lynne M. (Robert Gordon University School of Chemistry, 1990-06-01)
    TAYLOR, L.M. 1990. Interactions of platinum compounds with heterocyclic bases. Robert Gordon's Institute of Technology, PhD thesis.
    It is generally accepted that platinum antitumoar drugs bind, preferentially, to Guanine N7 in DNA. Thus the kinetics of formation and the energetics of dissociation of platinum-nitrogen bonding have been investigated, ...