Now showing items 1-2 of 2

  • Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. 

    Scipioni, Matteo; Kay, Graeme; Megson, Ian; Kong Thoo Lin, Paul (Elsevier https://doi.org/10.1016/j.ejmech.2017.11.072, 2017-12-02)
    SCIPIONI, M., KAY, G., MEGSON, I. and KONG THOO LIN, P. 2017. Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. European journal of medicinal chemistry [online], 143, pages 745-754. Available from: https://doi.org/10.1016/j.ejmech.2017.11.072
    Antioxidants have been the subject of intense research interest mainly due to their beneficial properties associated with human health and wellbeing. Phenolic molecules, such as naturally occurring Resveratrol and Vanillin, ...
  • Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer’s disease. 

    Scipioni, Matteo; Kay, Graeme; Megson, Ian; Kong Thoo Lin, Paul (Royal Society of Chemistry https://doi.org/10.1039/c9md00048h, 2019-04-08)
    SCIPIONI, M., KAY, G., MEGSON, I.L. and KONG THOO LIN, P. 2019. Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer’s disease. MedChemComm [online], (accepted). Available from: https://doi.org/10.1039/C9MD00048H
    Alzheimer’s Disease (AD) is the most common cause of dementia worldwide, normally affecting people aged over 65. Due to the multifactorial nature of this disease, a “multi-target-directed ligands” (MTDLs) approach for the ...