A novel method of producing microbubbles for targeted drug delivery.
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FIABANE, J. 2016. A novel method of producing microbubbles for targeted drug delivery. Robert Gordon University, PhD thesis.
Microbubbles, currently employed in diagnostic ultrasound as a contrast agent, have a potential new application as vehicles for targeted drug delivery, which could revolutionise medicine by eliminating side-effects. A new device is developed which outperforms all existing devices in terms of minimum microbubble size:channel diameter ratio. A numerical model is established to describe the flow behaviour and it is determined that the flow regime and resulting microbubble size are dependent on the ratio of inner- to outer Weber number.