Show simple item record

dc.contributor.authorDuthie, Susan J.
dc.contributor.authorDuthie, Garry G.
dc.contributor.authorRussell, Wendy R.
dc.contributor.authorKyle, Janet A. M.
dc.contributor.authorMacdiarmid, Jennie I.
dc.contributor.authorRungapamestry, Vanessa
dc.contributor.authorStephen, Sylvia
dc.contributor.authorMegias-Baeza, Cristina
dc.contributor.authorKaniewska, Joanna J.
dc.contributor.authorShaw, Lindsey
dc.contributor.authorMilne, Lesley
dc.contributor.authorBremner, David
dc.contributor.authorRoss, Karen
dc.contributor.authorMorrice, Philip
dc.contributor.authorPirie, Lynn P.
dc.contributor.authorHorgan, Graham
dc.contributor.authorBestwick, Charles S.
dc.date.accessioned2017-06-02T08:51:51Z
dc.date.available2017-06-02T08:51:51Z
dc.date.issued2017-05-30en
dc.identifier.citationDUTHIE, S.J., DUTHIE, G.G., RUSSELL, W.R., KYLE, J.A.M., MACDIARMID, J.I., RUNGAPAMESTRY, V., STEPHEN, S., MEGIAS-BAEZA, C., KANIEWSKA, J.J., SHAW, L., MILNE, L., BREMNER, D., ROSS, K., MORRICE, P., PIRIE, L.P., HORGAN, G. and BESTWICK, C.S. 2018. Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial. European journal of nutrition [online], 57(5), pages 1855-1872. Available from: https://doi.org/10.1007/s00394-017-1469-0en
dc.identifier.issn1436-6207en
dc.identifier.issn1436-6215en
dc.identifier.urihttp://hdl.handle.net/10059/2352
dc.description.abstractPurpose Low fruit and vegetable consumption is linked with an increased risk of death from vascular disease and cancer. The benefit of eating fruits and vegetables is attributed in part to antioxidants, vitamins and phytochemicals. Whether increasing intake impacts on markers of disease remains to be established. This study investigates whether increasing daily intake of fruits, vegetables and juices from low (approx. 3 portions), to high intakes (approx. 8 portions) impacts on nutritional and clinical biomarkers. Barriers to achieving the recommended fruit and vegetable intakes are also investigated. Method In a randomised clinical trial, the participants [19 men and 26 women (39–58 years)] with low reported fruit, juice and vegetable intake (<3 portions/day) were randomised to consume either their usual diet or a diet supplemented with an additional 480 g of fruit and vegetables and fruit juice (300 ml) daily for 12 weeks. Nutritional biomarkers (vitamin C, carotenoids, B vitamins), antioxidant capacity and genomic stability were measured pre-intervention, at 4-, 8- and 12 weeks throughout the intervention. Samples were also taken post-intervention after a 6-week washout period. Glucose, homocysteine, lipids, blood pressure, weight and arterial stiffness were also measured. Intake of fruit, fruit juice and vegetables was reassessed 12 months after conducting the study and a questionnaire was developed to identify barriers to healthy eating. Results Intake increased significantly in the intervention group compared to controls, achieving 8.4 portions/day after 12 weeks. Plasma vitamin C (35%), folate (15%) and certain carotenoids [α-carotene (50%) and β-carotene (70%) and lutein/zeaxanthin (70%)] were significantly increased (P < 0.05) in the intervention group. There were no significant changes in antioxidant capacity, DNA damage and markers of vascular health. Barriers to achieving recommended intakes of fruits and vegetables measured 12 months after the intervention period were amount, inconvenience and cost. Conclusion While increasing fruit, juice and vegetable consumption increases circulating level of beneficial nutrients in healthy subjects, a 12-week intervention was not associated with effects on antioxidant status or lymphocyte DNA damage.en
dc.description.sponsorshipScottish Government Rural and Environmental Science and Analytical Scinces Division, RankPrize Funds.en
dc.language.isoengen
dc.publisherSpringeren
dc.rightshttps://creativecommons.org/licenses/by/4.0en
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectFruiten
dc.subjectVegetablesen
dc.subjectHuman interventionen
dc.subjectDietary changeen
dc.subjectBiomarkersen
dc.subjectAttitudesen
dc.titleEffect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial.en
dc.typeJournal articlesen
dc.publisher.urihttps://doi.org/10.1007/s00394-017-1469-0en
dcterms.dateAccepted2017-05-06en
dcterms.publicationdate2018-08-31
refterms.accessExceptionNAen
refterms.dateDeposit2017-06-02en
refterms.dateFCA2017-05-30en
refterms.dateFCD2017-06-02en
refterms.dateFreeToDownload2017-05-30en
refterms.dateFreeToRead2017-05-30en
refterms.dateToSearch2017-05-30en
refterms.depositExceptionpublishedGoldOAen
refterms.panelAen
refterms.technicalExceptionNAen
refterms.versionVoRen
rioxxterms.publicationdate2017-05-30en
rioxxterms.typeJournal Article/Reviewen
rioxxterms.versionVoRen


Files in this item

This item appears in the following Collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0