The SIMPATHY (Stimulating Innovation Management of Polypharmacy and Adherence in The Elderly) project aims to tackle some of the challenges brought on by an ageing population, and to deliver the necessary change in management approaches and tools to help manage multi-medication and adherence to prescribed drugs. The project also looks to identify best practice across the EU in order to stimulate, promote and support innovation in the management of appropriate polypharmacy and adherence in the elderly. The project is co-funded by the Health Programme of the European Union (2014-2020, project 663082) and is led by the Scottish Government. The partners in the project form a consortium, constituting an interdisciplinary team that consists of pharmacists, health economists, and leading academic researchers in the fields of polypharmacy, medication adherence and multimorbidity. Targeted communication with key stakeholders is at the heart of SIMPATHY, helping to streamline and tailor information resulting from the project to those specific groups with the ability to effect change.

Recent Submissions

  • SIMPATHY project. [Project website] 

    SIMPATHY (Scottish Government Health and Social Care Directorates http://www.simpathy.eu/, 2015-01-01)
    SIMPATHY 2015. SIMPATHY project. Edinburgh: Scottish Government Health and Social Care Directories [online]. Available from: http://www.simpathy.eu
    This is the offical website for the SIMPATHY project. The SIMPATHY (Stimulating Innovation Management of Polypharmacy and Adherence in The Elderly) project aims to tackle some of the challenges brought on by an ageing ...
  • A case study of polypharmacy management in nine European countries: implications for change management and implementation. 

    McIntosh, Jennifer; Alonso, Albert; MacLure, Katie; Stewart, Derek C.; Kempen, Thomas; Mair, Alpana; Castel-Branco, Margarida; Codina, Carles; Fernandez-Llimos, Fernando; Fleming, Glenda; Gennimata, Dimitra; Gillespie, Ulrika; Harrison, Cathy; Illario, Maddalena; Junius-Walker, Ulrike; Kampolis, Christos F.; Kardas, Przemyslaw; Lewek, Pawel; Malva, Joao; Menditto, Enrica; Scullin, Claire; Wiese, Birgitt (Public Library of Science https://doi.org/10.1371/journal.pone.0195232, 2018-04-18)
    MCINTOSH, J., ALONSO, A., MACLURE, K., STEWART, D., KEMPEN, T., MAIR, A., CASTEL-BRANCO, M., CODINA, C., FERNANDEZ-LLIMOS, F., FLEMING, G., GENNIMATA, D., GILLESPIE, U., HARRISON, C., ILLARIO, M., JUNIUS-WALKER, U., KAMPOLIS, C.F., KARDAS, P., LEWEK, P., MALVA, J., MENDITTO, E., SCULLIN, C., WIESE, B. 2018. A case study of polypharmacy management in nine European countries: implications for change management and implementation. PLoS ONE [online], 13(4), e0195232. Available from: https://doi.org/10.1371/journal.pone.0195232
    Background: - Multimorbidity and its associated polypharmacy contribute to an increase in adverse drug events, hospitalizations, and healthcare spending. This study aimed to address: what exists regarding polypharmacy ...
  • Standardised quality assessment criteria and output evaluation plans for all WPs. 

    Stewart, Derek C.; MacLure, Katie; Wiese, Birgitt; Junius-Walker, Ulrike (SIMPATHY Consortium http://www.simpathy.eu/, 2015-09-28)
    STEWART, D., MACLURE, K., WIESE, B. and JUNIUS-WALKER, U. 2015. Standardised quality assessment criteria and output evaluation plans for all WPs. Edinburgh: SIMPATHY [online], Deliverable 3.1. Available from: http://www.simpathy.eu/
    Objectives: - The objectives relating to this deliverable are: 1) To develop communications channels between WP3 and WP leads. 2) To develop an internal reporting system for WP tasks, activities, progress with milestones ...
  • A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. 

    Stewart, Derek C.; Gibson Smith, Kathrine Lesley; MacLure, Katie; Mair, Alpana; Alonso, Albert; Codina, Carles; Cittadini, Antonio; Fernandez-Llimos, Fernando; Fleming, Glenda; Gennimata, Dimitra; Gillespie, Ulrike; Harrison, Cathy; Junius-Walker, Ulrika; Kardas, Przemyslaw; Kempen, Thomas; Kinnear, Moira; Lewek, Pawel; Malva, Joao; McIntosh, Jennifer; Scullin, Claire; Wiese, Birgitt (Public Library of Science https://doi.org/10.1371/journal.pone.0188348, 2017-11-20)
    STEWART, D., GIBSON-SMITH, K., MACLURE, K., MAIR, A., ALONSO, A., CODINA, C., CITTADINI, A., FERNANDEZ-LLIMOS, F., FLEMING, G., GENNIMATA, D., GILLESPIE, U., HARRISON, C., JUNIUS-WALKER, U., KARDAS, P., KEMPEN, T., KINNEAR, M., LEWEK, P., MALVA, J., MCINTOSH, J., SCULLIN, C. and WIESE, B. 2017. A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. PLoS ONE [online], 12(11), e0188348. Available from: https://doi.org/10.1371/journal.pone.0188348
    Background:- Inappropriate use of multiple medicines (inappropriate polypharmacy) is a major challenge in older people with consequences of increased prevalence and severity of adverse drug reactions and interactions, and ...
  • Polypharmacy management by 2030: a patient safety challenge. 

    Mair, Alpana; Fernandez-Llimos, Fernando; Alonso, Albert; Harrison, Cathy; Hurding, Simon; Kempen, Thomas; Kinnear, Moira; Michael, Nils; McIntosh, Jennifer; Wilson, Martin; SIMPATHY Consortium (SIMPATHY Consortium http://www.simpathy.eu/resources/publications/simpathy-project-reference-book, 2017-04-30)
    MAIR, A., FERNANDES-LLIMOS, F., ALONSO, A., HARRISON, C., HURDING, S., KEMPEN, T., KINNEAR, M., MICHAEL, N., MCINTOSH, J., WILSON, M. and the SIMPATHY consortium. 2017. Polypharmacy management by 2030: a patient safety challenge. Edinburgh: SIMPATHY CONSORTIUM [online]. Available from: http://www.simpathy.eu/resources/publications/simpathy-project-reference-book
    The SIMPATHY (Stimulating Innovation Management of Polypharmacy and Adherence in The Elderly) consortium have explored how healthcare management programmes can be implemented to improve medication safety and prevent patient ...
  • Guidance to manage inappropriate polypharmacy in older people: systematic review and future developments. 

    Stewart, Derek C.; Mair, Alpana; Wilson, Martin; Kardas, Przemyslaw; Lewek, Pawel; Alonso, Albert; McIntosh, Jennifer; MacLure, Katie; SIMPATHY Consortium (Taylor and Francis https://doi.org/10.1080/14740338.2017.1265503, 2016-12-04)
    STEWART, D., MAIR, A., WILSON, M., KARDAS, P., LEWEK, P., ALONSO, A., MCINTOSH, J., MACLURE, K. and SIMPATHY Consortium. 2017. Guidance to manage inappropriate polypharmacy in older people: systematic review and future developments. Expert opinion on drug safety [online], 16(2), pages 203-213. Available from: https://doi.org/10.1080/14740338.2017.1265503
    Introduction: Single disease state led evidence-based guidelines do not provide sufficient coverage of issues of multimorbidities, with the cumulative impact of recommendations often resulting in overwhelming medicines ...