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dc.contributor.authorDolan, Eimear
dc.contributor.authorSwinton, Paul Alan
dc.contributor.authorSale, Craig
dc.contributor.authorHealy, Aoife
dc.contributor.authorO'Reilly, John
dc.date.accessioned2017-11-21T11:40:52Z
dc.date.available2017-11-21T11:40:52Z
dc.date.issued2017-09-28en
dc.identifier.citationDOLAN, E., SWNTON, P.A., SALE, C., HEALY, A. and O'REILLY, J. 2017. Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis. Nutrition reviews [online], 75(10), pagers 858-870. Available from: https://doi.org/10.1093/nutrit/nux046en
dc.identifier.issn0029-6643en
dc.identifier.issn1753-4887en
dc.identifier.urihttp://hdl.handle.net/10059/2596
dc.descriptionJOURNAL ARTICLES. The original Systematic Review Protocol for this is available from http://hdl.handle.net/10059/2806
dc.description.abstractContext: The scientific literature shows conflicting evidence about the relationship between adiposity and bone mass in overweight and obese populations. Objective: The aim of this review was to quantify the correlation between adipose mass (absolute and relative) and bone mineral density (BMD) in overweight and obese populations. Data Sources: Three databases were searched electronically. In addition, reference lists of relevant articles were screened. Study Selection: A total of 16 studies, comprising 2587 participants and 75 correlation coefficients were selected for inclusion in the review. Data Extraction: Data were extracted from each study using a standardized form. Results: Multilevel modeling indicated opposing relationships between BMD and adiposity: absolute adiposity correlated positively, and relative adiposity negatively, with BMD. Sex and age were the primary moderators of these relationships. Strong evidence supported a negative relationship between relative adipose mass and BMD in men (R = −0.37; 95%CI, −0.57 to −0.12) and in those aged less than 25 years (R = −0.28; 95%CI, −0.45 to −0.08). Conclusion: To prevent bone loss in overweight and obese populations, nutrition- and exercise-based interventions that focus on a controlled reduction of adipose mass with concomitant preservation of lean mass are recommended. Systematic Review Registration: PROSPERO no. CRD42015024313. Please note that the title on this manuscript differs from the published version.en
dc.description.sponsorshipHong Kong-Scotland Partners in Post Doctoral Research program ; Fundacao de Amparoa Pesquisa do Estado de Sao Paulo (FAPESP) [2015/11328-2].en
dc.language.isoengen
dc.publisherOUPen
dc.relation.urihttp://hdl.handle.net/10059/2806
dc.rightshttps://creativecommons.org/licenses/by-nc/4.0en
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectAdiposityen
dc.subjectBody compositionen
dc.subjectBone massen
dc.subjectChronic conditionen
dc.subjectObesityen
dc.subjectOsteoporosisen
dc.subjectNutritionen
dc.titleInfluence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis.en
dc.typeJournal articlesen
dc.publisher.urihttps://doi.org/10.1093/nutrit/nux046en
dcterms.dateAccepted2017-09-28en
dcterms.publicationdate2017-10-01en
refterms.accessExceptionNAen
refterms.dateDeposit2017-11-21en
refterms.dateEmbargoEnd2018-09-28en
refterms.dateFCA2018-09-28en
refterms.dateFCD2017-11-21en
refterms.dateFreeToDownload2018-09-28en
refterms.dateFreeToRead2018-09-28en
refterms.dateToSearch2018-09-28en
refterms.depositExceptionNAen
refterms.panelAen
refterms.technicalExceptionNAen
refterms.versionAMen
rioxxterms.publicationdate2017-09-28en
rioxxterms.typeJournal Article/Reviewen
rioxxterms.versionAMen


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