Recent Submissions

  • Why is so much clinical research ignored and what can we do about it? 

    Grant, Aileen; Treweek, Shaun; Wells, Mary (Mark Allen Healthcare https://doi.org/10.12968/hmed.2016.77.10.554, 2016-10-10)
    GRANT, A., TREWEEK, S. and WELLS, M. 2016. Why is so much clinical research ignored and what can we do about it? British journal of hospital medicine [online], 77(10), pages 554-555. Available from: https://doi.org/10.12968/hmed.2016.77.10.554
    The key points of this article are 1) Research evidence from clinical trials is not being translated into clinical practice in a timely manner and this represents an enormous waste of resources and missed opportunities. ...
  • Embedding knowledge transfer to increase productivity in school nursing. 

    Forkuo, Anthony Kwaku (Mark Allen Healthcare https://doi.org/10.12968/bjsn.2017.12.10.480, 2017-12-15)
    FORKUO, A.K. 2017. Embedding knowledge transfer to increase productivity in school nursing. British journal of school of nursing [online], 12(10), pages 480-484. Available from: https://doi.org/10.12968/bjsn.2017.12.10.480
    This article is a discussion paper aimed at school nursing leaders and, importantly, nursing managers and academics who are looking for ways to sustain nursing services. With austerity, there is a compelling demand for ...
  • Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: case study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing. 

    Grant, Aileen; Dreischulte, Tobias; Guthrie, Bruce (BMJ Publishing Group https://doi.org/10.1136/bmjopen-2016-015281, 2017-03-01)
    GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2017. Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: case study evaluation of adoption and maintenance of a complex intervention to reduce high-risk primary care prescribing. BMJ open [online], 7(3), article ID e015281. Available from: https://doi.org/10.1136/bmjopen-2016-015281
    Objective: - To explore how different practices responded to the Data-driven Quality Improvement in Primary Care (DQIP) intervention in terms of their adoption of the work, reorganisation to deliver the intended change in ...
  • Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing. 

    Grant, Aileen; Dreischulte, Tobias; Guthrie, Bruce (BioMed Central https://doi.org/10.1186/s13012-016-0531-2, 2017-01-07)
    GRANT, A., DREISCHULTE, T. and GUTHRIE, B. 2017. Process evaluation of the data-driven quality improvement in primary care (DQIP) trial: active and less active ingredients of a multi-component complex intervention to reduce high-risk primary care prescribing. Implementation science [online], 12, article ID 4. Available from https://doi.org/10.1186/s13012-016-0531-2
    Background: - Two to 4% of emergency hospital admissions are caused by preventable adverse drug events. The estimated costs of such avoidable admissions in England were £530 million in 2015. The data-driven quality improvement ...
  • Assessing the multidimensional relationship between medication beliefs and adherence in older adults with hypertension using polynomial regression. 

    Dillon, Paul; Phillips, L. Alison; Gallagher, Paul; Smith, Susan M.; Stewart, Derek C.; Cousins, Grainne (OUP https://doi.org/10.1093/abm/kax016, 2018-01-11)
    DILLON, P., PHILLIPS, L.A., GALLAGHER, P., SMITH, S.M., STEWART, D., COUSINS, G. 2018. Assessing the multidimensional relationship between medication beliefs and adherence in older adults with hypertension using polynomial regression. Annals of behavioral medicine [online], Advanced Articles. Available from: https://doi.org/10.1093/abm/kax016
    Background: - The Necessity-Concerns Framework (NCF) is a multidimensional theory describing the relationship between patients' positive and negative evaluations of their medication which interplay to influence adherence. ...
  • Zinc-modified nanotransporter of doxorubicin for targeted prostate cancer delivery. 

    Skalickova, Sylvie; Loffelmann, Martin; Gargulak, Michael; Kepinska, Marta; Docekalova, Michaela; Uhlirova, Dagmar; Stankova, Martina; Fernandez, Carlos; Milnerowicz, Halina; Ruttkay-Nedecky, Branislav; Kizek, Rene (MDPI https://doi.org/10.3390/nano7120435, 2017-12-08)
    SKALICKOVA, S., LOFFELMANN, M., GARGULAK, M., KEPINSKA, M., DOCEKALOVA, M., UHLIROVA, D., STANKOVA, M., FERNANDEZ, C., MILNEROWICZ, H., RUTTKAY-NEDECKY, B. and KIZEK, R. 2017. Zinc-modified nanotransporter of doxorubicin for targeted prostate cancer delivery. Nanomaterials [online], 7(12), article ID 435. Available from: https://doi.org/10.3390/nano7120435
    This work investigated the preparation of chitosan nanoparticles used as carriers for doxorubicin for targeted cancer delivery. Prepared nanocarriers were stabilized and functionalized via zinc ions incorporated into the ...
  • Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: quantitative examination of variation between practices in recruitment, implementation and effectiveness. 

    Dreischulte, Tobias; Grant, Aileen; Hapca, Adrian; Guthrie, Bruce (BMJ Publishing Group https://doi.org/10.1136/bmjopen-2017-017133, 2018-01-05)
    DREISCHULTE, T., GRANT, A., HAPCA, A. and GUTHRIE, B. 2018. Process evaluation of the Data-driven Quality Improvement in Primary Care (DQIP) trial: quantitative examination of variation between practices in recruitment, implementation and effectiveness. BMJ open [online], 8(1), article ID e017133. Available from: https://doi.org/10.1136/bmjopen-2017-017133
    Objectives: - The cluster randomised trial of the Data-driven Quality Improvement in Primary Care (DQIP) intervention showed that education, informatics and financial incentives for general medical practices to review ...
  • The experiences and beliefs of older people in Scottish very sheltered housing about using multi-compartment compliance aids. 

    Stewart, Derek C.; Gibson-Smith, Kathrine; MacLeod, Joan; Strath, Alison; Paudyal, Vibhu; Forbes-McKay, Katrina
    STEWART, D., GIBSON-SMITH, K., MACLEOD, J., STRATH, A., PAUDYAL, V. and FORBES-MCKAY, K. [2018]. The experiences and beliefs of older people in Scottish very sheltered housing about using multi-compartment compliance aids. International journal of clinical pharmacy [online], (accepted). Available from: https://doi.org/10.1007/s11096-017-0580-x
    The aim was to describe the experiences and beliefs of older people surrounding the use of MCAs, with emphasis on issues of personalisation, reablement, shared decision-making, independence and support. This was a qualitative ...
  • Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey. 

    McLay, James S.; Izzati, Naila; Pallivalapila, Abdul R.; Shetty, Ashalatha; Pande, Binita; Rore, Craig; Al Hail, Moza; Stewart, Derek C. (BioMed Central https://doi.org/10.1186/s12906-017-2052-1, 2017-12-19)
    MCLAY, J.S., IZZATI, N., PALLIVALAPILA, A.R., SHETTY, A., PANDE, B., RORE, C., AL HAIL, M. and STEWART, D. 2017. Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey. BMC complementary and alternative medicine [online], 17, article ID 543. Available from: https://doi.org/10.1186/s12906-017-2052-1
    Background: - Pregnant women are routinely prescribed medicines while self-medicating with herbal natural products to treat predominantly pregnancy related conditions. The aim of this study was to assess the potential for ...
  • Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. 

    Turner, Andrew D.; Waack, Julia; Lewis, Adam; Edwards, Christine; Lawton, Linda A. (Elsevier https://doi.org/10.1016/j.jchromb.2017.12.032, 2017-12-28)
    TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2017. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], In Press. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032
    A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, ...
  • A woman's hand and a lion's heart: Skills and attributes for rural midwifery practice in New Zealand and Scotland. 

    Gilkison, Andrea; Rankin, Jean; Kensington, Mary; Daellenbach, Rea; Davies, Lorna; Deery, Ruth; Crowther, Susan (Elsevier https://doi.org/10.1016/j.midw.2017.12.009, 2017-12-19)
    GILKISON, A., RANKIN, J., KENSINGTON, M., DAELLENBACH, R., DAVIES, L., DEERY, R. and CROWTHER, S. 2017. A woman's hand and a lion's heart: Skills and attributes for rural midwifery practice in New Zealand and Scotland. Midwifery [online], In Press. Available from: https://doi.org/10.1016/j.midw.2017.12.009
    Objective:- The complex and challenging nature of rural midwifery is a global issue. New Zealand and Scotland both face similar ongoing challenges in sustaining a rural midwifery workforce, and understanding the best ...
  • A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. 

    Stewart, Derek C.; Gibson-Smith, Kathrine; MacLure, Katie; Mair, Alpana; Alonso, Albert; Codina, Carles; Cittadini, Antonio; Fernandez-Llimos, Fernando; Fleming, Glenda; Gennimata, Dimitra; Gillespie, Ulrika; Harrison, Cathy; Junius-Walker, Ulrika; Kardas, Przemyslaw; Kempen, Thomas; Kinnear, Moira; Lewek, Pawel; Malva, Joao; McIntosh, Jennifer; Scullin, Claire; Wiese, Birgitt (Public Library of Science https://doi.org/10.1371/journal.pone.0188348, 2017-11-20)
    STEWART, D., GIBSON-SMITH, K., MACLURE, K., MAIR, A., ALONSO, A., CODINA, C., CITTADINI, A., FERNANDEZ-LLIMOS, F., FLEMING, G., GENNIMATA, D., GILLESPIE, U., HARRISON, C., JUNIUS-WALKER, U., KARDAS, P., KEMPEN, T., KINNEAR, M., LEWEK, P., MALVA, J., MCINTOSH, J., SCULLIN, C. and WIESE, B. 2017. A modified Delphi study to determine the level of consensus across the European Union on the structures, processes and desired outcomes of the management of polypharmacy in older people. PLoS ONE [online], 12(11), e0188348. Available from: https://doi.org/10.1371/journal.pone.0188348
    Background:- Inappropriate use of multiple medicines (inappropriate polypharmacy) is a major challenge in older people with consequences of increased prevalence and severity of adverse drug reactions and interactions, and ...
  • Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. 

    Ibie, Chidinma O.; Thompson, Colin J.; Knott, Rachel M. (Springer https://doi.org/10.1007/s00396-015-3561-4, 2015-03-24)
    IBIE, C.O., THOMPSON, C.J. and KNOTT, R. 2015. Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. Colloid and polymer science [online], 293(6), pages 1737-1748. Available from: https://doi.org/10.1007/s00396-015-3561-4
    Polyallylamine (Paa) was quaternised by methylation of its primary amines using methyl iodide to yield quaternised Paa (QPaa). Average level of polymer quaternisation was determined by elemental analysis and was found to ...
  • In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. 

    Ibie, Chidinma O.; Knott, Rachel M.; Thompson, Colin J. (Elsevier https://doi.org/10.1016/j.ijpharm.2014.12.058, 2014-12-27)
    IBIE, C., KNOTT, R. and THOMPSON, C.J. 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International journal of pharmaceutics [online], 479(1), pages 103-117. Available from: https://doi.org/10.1016/j.ijpharm.2014.12.058
    The biocompatibility and cellular uptake of polymer, insulin polyelectrolyte complexes (PECs) prepared using polyallylamine-based polymers was evaluated in-vitro using Caco-2 cell monolayers as a predictive model for human ...
  • Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. 

    Scipioni, Matteo; Kay, Graeme; Megson, Ian; Kong Thoo Lin, Paul (Elsevier https://doi.org/10.1016/j.ejmech.2017.11.072, 2017-12-02)
    SCIPIONI, M., KAY, G., MEGSON, I. and KONG THOO LIN, P. 2017. Novel vanillin derivatives: synthesis, anti-oxidant, DNA and cellular protection properties. European journal of medicinal chemistry [online], 143, pages 745-754. Available from: https://doi.org/10.1016/j.ejmech.2017.11.072
    Antioxidants have been the subject of intense research interest mainly due to their beneficial properties associated with human health and wellbeing. Phenolic molecules, such as naturally occurring Resveratrol and Vanillin, ...
  • Users' perceptions of interprofessional collaborative care during their cancer journeys'. 

    Joseph, Sundari Catherine; Barnard, S.; Macduff, Colin; Moffat, M.; Walker, P.; Diack, Lesley (eSciRes https://doi.org/10.0000/JHSE.1000122, 2017-11-14)
    JOSEPH, S., BARNARD, S., MACDUFF, C., MOFFAT, M., WALKER, P. and DIACK, L. 2017. Users' perceptions of interprofessional collaborative care during their cancer journeys'. Journal of health science and education [online], 1(3), pages 1-11. Available from: http://escires.com/articles/Health-1-122.pdf
    Purpose: The study aimed to construct narratives of journeys that cancer patients and their families experience and to investigate participants' perceptions of related interagency collaboration spanning any engagements ...
  • Monitoring content of cadmium, calcium, copper, iron, lead, magnesium and manganese in tea leaves by electrothermal and flame atomizer atomic absorption spectrometry 

    Prkic, Ante; Juric, Antonija; Giljanovic, Josipa; Politeo, Nives; Sokol, Vesna; Boskovic, Perica; Brkljaca, Mia; Stipisic, Angela; Fernandez, Carlos; Vukusic, Tina (De Gruyter https://doi.org/10.1515/chem-2017-0023, 2017-08-16)
    PRKIC, A., JURIC, A., GILJANOVIC, J., POLITEO, N., SOKOL, V., BOSKOVIC, P., BRKLJACA, M., STIPISIC, A., FERNANDEZ, C. and VUKUSIC, T. 2017. Monitoring content of cadmium, calcium, copper, iron, lead, magnesium and manganese in tea leaves by electrothermal and flame atomizer atomic absorption spectrometry. Open chemistry [online], 15(1), pages 200-207. Available from: https://doi.org/10.1515/chem-2017-0023
    Due to the simplicity of tea preparation (pouring hot water onto different dried herbs) and its high popularity as a beverage, monitoring and developing a screening methodology for detecting the metal content is very ...
  • Combining stable isotopes with contamination indicators: A method for improved investigation of nitrate sources and dynamics in aquifers with mixed nitrogen inputs. 

    Minet, Eddy P.; Goodhue, R.; Meier-Augenstein, Wolfram; Kalin, R. M.; Fenton, O.; Richards, K. G.; Coxon, Catherine E. (Elsevier https://doi.org/10.1016/j.watres.2017.07.041, 2017-07-18)
    MINET, E.P., GOODHUE, R., MEIER-AUGENSTEIN, W., KALIN, R.M., FENTON, O., RICHARDS, K.G. and COXON, C.E. 2017. Combining stable isotopes with contamination indicators: A method for improved investigation of nitrate sources and dynamics in aquifers with mixed nitrogen inputs. Water research [online], 124, pages 85-96. Available from: https://doi.org/10.1016/j.watres.2017.07.041
    Excessive nitrate (NO3−) concentration in groundwater raises health and environmental issues that must be addressed by all European Union (EU) member states under the Nitrates Directive and the Water Framework Directive. ...
  • Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: a systematic review and meta-regression. 

    Deb, Sanjoy K.; Brown, Daniel R.; Gough, Lewis A.; McLellan, Christopher P.; Swinton, Paul Alan; Sparks, S. Andy; McNaughton, Lars R. (Taylor and Francis https://doi.org/10.1080/17461391.2017.1410233, 2017-12-08)
    DEB, S.K., BROWN, D.R., GOUGH, L.A., MCLELLAN, C.P., SWINTON, P.A., SPARKS, S.A. and MCNAUGHTON, L.R. 2017. Quantifying the effects of acute hypoxic exposure on exercise performance and capacity: a systematic review and meta-regression. European journal of sport science [online], Latest Articles. Available from: https://doi.org/10.1080/17461391.2017.1410233
    Objective: To quantify the effects of acute hypoxic exposure on exercise capacity and performance, which includes continuous and intermittent forms of exercise. Design: A systematic review was conducted with a three-level ...
  • Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis. 

    Dolan, Eimear; Swinton, Paul Alan; Sale, Craig; Healy, Aoife; O'Reilly, John (OUP https://doi.org/10.1093/nutrit/nux046, 2017-09-28)
    DOLAN, E., SWNTON, P.A., SALE, C., HEALY, A. and O'REILLY, J. 2017. Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis. Nutrition reviews [online], 75(10), pagers 858-870. Available from: https://doi.org/10.1093/nutrit/nux046
    Context: The scientific literature shows conflicting evidence about the relationship between adiposity and bone mass in overweight and obese populations. Objective: The aim of this review was to quantify the correlation ...

View more