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  • Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease. 

    Gaspar, Luis; Coron, Ross P.; Kong Thoo Lin, Paul; Costa, David M.; Peres-Cabezas, Begona; Tavares, Joana; Roura-Ferrer, Meritxell; Ramos, Isbaal; Ronin, Celine; Major, Louise L.; Ciesielski, Fabrice; Pemberton, Ian K.; MacDougall, Jane; Ciapetti, Paola; Smith, Terry K.; Cordeiro-da-Silva, Anabela (Public Library of Science https://doi.org/10.1371/journal.pntd.0006180, 2018-01-22)
    GASPAR, L., CORON, R.P., KONG THOO LIN, P., COSTA, D.M., PERES-CABEZAS, B., TAVARES, J., ROURA-FERRER, M., RAMOS, I., RONIN, C., MAJOR, L.L., CIESIELSKI, F., PEMBERTON, I.K., MACDOUGALL, J., CIAPETTI, P., SMITH, T.K. and CORDEIRO-DA-SILVA, A. 2018. Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease. PLoS neglected tropical diseases [online], 12(1), article ID e0006180. Available from: https://doi.org/10.1371/journal.pntd.0006180
    Chagas disease remains one of the most neglected diseases in the world despite being the most important parasitic disease in Latin America. The characteristic chronic manifestation of chagasic cardiomyopathy is the region’s ...