Recent Submissions

  • Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping. 

    Skujina, Ilze; Winton, Clare Louise; Hegarty, Matthew J.; McMahon, Robert; Nash, Deborah Mary; Davies-Morel, Mina Clare Gwynne; McEwan, Neil R.
    SKUJINA, I., WINTON, C.L., HEGARTY, M.J., MCMAHON, R., NASH, D.M., DAVIES-MOREL, M.C.G. and MCEWAN, N.R. [2018]. Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping. Genome [online], (accepted).
    Height is an important characteristic in the equine industry although little is known about its genetic control in native British breeds of ponies. This study aimed to map QTL data with the withers height in 4 pony breeds ...
  • Unique corrosion resistance of ultrahigh pressure Mg-25Al binary alloys. 

    Feng, Jiawen; Li, Hanning; Deng, Kunkun; Fernandez, Carlos; Zhang, Qingrui; Peng, Qiuming (Elsevier https://doi.org/10.1016/j.corsci.2018.08.013, 2018-08-15)
    FENG, J., LI, H., DENG, K., FERNANDEZ, C., ZHANG, Q. and PENG, Q. 2018. Unique corrosion resistance of ultrahigh pressure Mg-25Al binary alloys. Corrosion science [online], In Press. Available from: https://doi.org/10.1016/j.corsci.2018.08.013
    Differing from as-cast and solid-solution alloys with coarse eutectic phases (Mg17Al12), a single-phase structure is attained in Mg-25wt.%Al alloy after ultrahigh-pressure solid-solution (USS, 800 oC, 4GPa). This USSed ...
  • In-situ atomic-scale phase transformation of Mg under hydrogen conditions. 

    Peng, Qiuming; Sun, Yong; Ge, Bincheng; Feng, Jiawen; Guo, Jianxin; Fernandez, Carlos; Huang, Jianyu (American Chemical Society https://doi.org/10.1021/acs.jpcc.8b04694, 2018-08-09)
    PENG, Q., SUN, Y., GE, B., FENG, J., GUO, J., FERNANDEZ, C. and HUANG, J. [2018]. In-situ atomic-scale phase transformation of Mg under hydrogen conditions. Journal of physical chemistry C [online], (accepted). Available from: https://doi.org/10.1021/acs.jpcc.8b04694
    Magnesium hydrogenation issue poses a serious obstacle to designing strong and reliable structural materials, as well as offering a safe alternative for hydrogen applications. Understanding phase transformation of magnesium ...
  • Comparative genetic diversity in a sample of pony breeds from the UK and North America: a case study in the conservation of global genetic resources. 

    Winton, Clare Louise; Plante, Yves; Hind, Pamela; McMahon, Robert; Hegarty, Matthew J.; McEwan, Neil R.; Davies-Morel, Mina Clare Gwynne; Morgan, Charly M.; Powell, Wayne; Nash, Deborah Mary (Wiley https://doi.org/10.1002/ece3.1562, 2015-07-31)
    WINTON, C.L., PLANTE, Y., HIND, P., MCMAHON, R., HEGARTY, M.J., MCEWAN, N.R., DAVIES-MOREL, M.C.G., MORGAN, C.M., POWELL, W. and NASH, D.M. 2015. Comparative genetic diversity in a sample of pony breeds from the UK and North America: a case study in the conservation of global genetic resources. Ecology and evolution [online], 5(16), pages 3507-3522. Available from: https://doi.org/10.1002/ece3.1562
    Most species exist as subdivided ex situ daughter population(s) derived from a single original group of individuals. Such subdivision occurs for many reasons both natural and manmade. Traditional British and Irish pony ...
  • Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. 

    Bestwick, Charles S.; Milne, Lesley; Dance, Anne-Marie; Cochennec, Gaela; Cruickshank, Gillian; Allain, Eflamm; Constable, Lynda; Duthie, Susan J.; Kong Thoo Lin, Paul (Elsevier https://doi.org/10.1016/j.tiv.2018.06.023, 2018-07-23)
    BESTWICK, C., MILNE, L., DANCE, A.-M., COCHENNEC, G., CRUICKSHANK, G., ALLAIN, E., CONSTABLE, L., DUTHIE, S. and KONG THOO LIN, P. 2018. Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells. Toxicology in vitro [online], 52, pages 342-350. Available from: https://doi.org/10.1016/j.tiv.2018.06.023
    Bisnaphthalimides are DNA intercalators of potential use as chemotherapeutics but for which the range of mechanism of action is only gradually being elucidated. Using human promyelocytic HL-60 cells, we extend characterization ...
  • Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. 

    Antoniou, Maria G.; Boraei, I.; Solakidou, M.; Deligiannakis, Y.; Abhishek, Mahalakshmi; Lawton, Linda A.; Edwards, Christine (Elsevier https://doi.org/10.1016/j.jhazmat.2018.07.111, 2018-08-03)
    ANTONIOU, M.G., BORAEI, I., SOLAKIDOU, M., DELIGIANNAKIS, Y., ABHISHEK, M., LAWTON, L.A. and EDWARDS, C. 2018. Enhancing photocatalytic degradation of the cyanotoxin microcystin-LR with the addition of sulfate-radical generating oxidants. Journal of hazardous materials [online], (accepted). Available from: https://doi.org/10.1016/j.jhazmat.2018.07.111
    This study investigated the coupling of sulfate radical generating oxidants, (persulfate, PS and peroxymonosulfate, PMS) with TiO2 photocatalysis for the degradation of microcystin-LR (MC-LR). Treatment efficiency was ...
  • Microbial diversity in the digestive tract of two different breeds of sheep. 

    Douglas, Jamie-Leigh; Worgan, Hilary J.; Easton, G. L.; Poret, L.; Wolf, B. T.; Edwards, A.; Davies, E.; Ross, D.; McEwan, Neil R. (Wiley https://doi.org/10.1111/jam.13060, 2016-01-19)
    DOUGLAS, J.-L., WORGAN, H.J., EASTON, G.L., PORET, L., WOLF, B.T., EDWARDS, A., DAVIES, E., ROSS, D. and MCEWAN, N.R. 2016. Microbial diversity in the digestive tract of two different breeds of sheep. Journal of applied microbiology [online], 120(5), pages 1382-1389. Available from: https://doi.org/10.1111/jam.13060
    Aims: This work aims to determine the factors which play a role in establishing the microbial population throughout the digestive tract in ruminants and is necessary to enhance our understanding of microbial establishment ...
  • Assessment of genetic relationship between six populations of Welsh Mountain sheep using microsatellite markers. 

    Huson, Kathryn M.; Haresign, W.; Hegarty, Matthew J.; Blackmore, T. M.; Morgan, C.; McEwan, Neil R. (CAAS (Czech Academy of Agricultural Sciences) https://doi.org/10.17221/8171-CJAS, 2015-05-31)
    HUSON, K.M., HARESIGN, W., HEGARTY, M.J., BLACKMORE, T.M., MORGAN, C. and MCEWAN, N.R. 2015. Assessment of genetic relationship between six populations of Welsh Mountain sheep using microsatellite markers. Czech journal of animal science [online], 60(5), pages 216-223. Available from: https://doi.org/10.17221/8171-CJAS
    This study investigated the genetic relationship between 6 populations of Welsh Mountain sheep: 5 phenotypic breed-types within the Welsh Mountain (WM) sheep breed, which have each been bred in specific geographic areas ...
  • In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. 

    Edmunds, J. L.; Worgan, Hilary J.; Dougal, Kirsty; Girdwood, Susan E.; Douglas, Jamie-Leigh; McEwan, Neil R. (Japanese Society of Equine Science https://doi.org/10.1294/jes.27.49, 2016-06-21)
    EDMUNDS, J.L., WORGAN, H.J., DOUGAL, K., GIRDWOOD, S.E., DOUGLAS, J.-L. and MCEWAN, N.R. 2016. In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. Journal of equine science [online], 27(2), pages 49-55. Available from: https://doi.org/10.1294/jes.27.49
    The present study uses in vitro analytical techniques to investigate the effect of activated charcoal on the microbial community of the equine hindgut and the metabolites they produce. Incubations were performed in Wheaton ...
  • Effect of entodinium caudatum on starch intake and glycogen formation by eudiplodinium maggii in the rumen and reticulum. 

    Bełżecki, Grzegorz; McEwan, Neil R.; Kowalik, Barabara; Michałowski, Tadeusz; Miltko, Renata (Elsevier http://dx.doi.org/10.1016/j.ejop.2016.09.007, 2016-10-12)
    BEŁŻECKI, G., MCEWAN, N.R., KOWALIK, B., MICHAŁOWSKI, T. and MILTKO, R. 2017. Effect of entodinium caudatum on starch intake and glycogen formation by eudiplodinium maggii in the rumen and reticulum. European journal of protistology [online], 57, pages 38-49. Available from: http://dx.doi.org/10.1016/j.ejop.2016.09.007
    This study aimed to quantify the engulfed starch and reserve α-glucans (glycogen) in the cells of the ciliates Eudiplodinium maggii, as well the α-glucans in defaunated and selectively faunated sheep. The content of starch ...
  • Genome sequence of human rhinovirus A22, strain Lancaster/2015. 

    Atkinson, Kate V.; Bishop, Lisa A.; Rhodes, Glenn; Salez, Nicolas; McEwan, Neil R.; Hegarty, Matthew J.; Robey, Julie; Harding, Nicola; Wetherell, Simon; Lauder, Robert M.; Pickup, Roger W.; Wilkinson, Mark; Gatherer, Derek (American Society for Microbiology https://doi.org/10.1128/genomeA.01713-16, 2017-03-23)
    ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Genome sequence of human rhinovirus A22, strain Lancaster/2015. Genome announcements [online], 5(12), article ID e01713-16. Available from: https://doi.org/10.1128/genomeA.01713-16
    The genome of human rhinovirus A22 (HRV-A22) was assembled by deep sequencing RNA samples from nasopharyngeal swabs. The assembled genome is 8.7% divergent from the HRV-A22 reference strain over its full length, and it is ...
  • Genome sequence of human papillomavirus 23 strain HPV-23/Lancaster/2015. 

    Atkinson, Kate V.; Bishop, Lisa A.; Rhodes, Glenn; Salez, Nicolas; McEwan, Neil R.; Hegarty, Matthew J.; Robey, Julie; Harding, Nicola; Wetherell, Simon; Lauder, Robert M.; Pickup, Roger W.; Wilkinson, Mark; Gatherer, Derek (American Society for Microbiology https://doi.org/10.1128/genomeA.00257-17, 2017-05-18)
    ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W, WILKINSON, M. and GATHERER, D. 2017. Genome sequence of human papillomavirus 23 strain HPV-23/Lancaster/2015. Genome announcements [online], 5(20), e00257-17. Available from: https://doi.org/10.1128/genomeA.00257-17
    The genome of human papillomavirus type 23 (HPV-23; family Papillomaviridae, genus Betapapillomavirus, species Betapapillomavirus 2, type 23) was assembled by deep sequencing from nasopharyngeal swabs. The assembled genome ...
  • Comparison of the microbial population in rabbits and guinea pigs by next generation sequencing. 

    Crowley, Edward J.; King, Jonathan M.; Wilkinson, Toby; Worgan, Hilary J.; Huson, Kathryn M.; Rose, Michael T.; McEwan, Neil R. (Public Library of Science https://doi.org/10.1371/journal.pone.0165779, 2017-02-09)
    CROWLEY, E.J., KING, J.M., WILKINSON, T., WORGAN, H.J., HUSON, K.M., ROSE, M.T. and MCEWAN, N.R. 2017. Comparison of the microbial population in rabbits and guinea pigs by next generation sequencing. PLOS one [online], 12(2), e0165779. Available from: https://doi.org/10.1371/journal.pone.0165779
    This study aimed to determine the microbial composition of faeces from two groups of caecotrophagic animals; rabbits and guinea pigs. In addition the study aimed to determine the community present in the different organs ...
  • An initial exploration of the perceptions of preparedness to practise among Saudi Arabian trained hospital pharmacists. 

    Ameer, Luma; MacLure, Katie; Tonna, Antonella P.; Stewart, Derek C. (CIPF https://doi.org/10.18549/PharmPract.2018.02.1192, 2018-06-26)
    AMEER, L., MACLURE, K., TONNA, A. and STEWART, D. 2018. An initial exploration of the perceptions of preparedness to practise among Saudi Arabian trained hospital pharmacists. Pharmacy practice [online], 16(2), article 1192. Available from: https://doi.org/10.18549/PharmPract.2018.02.1192
    Background: There is a dearth of literature on perceptions of preparedness to practise, which explores the extent to which educational institutions prepare their students to fulfil their professional role. Objective: The ...
  • Sequence variation in multidrug-resistant plasmid pLUH01, isolated from human nasopharyngeal swabs. 

    Atkinson, Kate V.; Bishop, Lisa A.; Rhodes, Glenn; Salez, Nicolas; McEwan, Neil R.; Hegarty, Matthew J.; Robey, Julie; Harding, Nicola; Wetherell, Simon; Lauder, Robert M.; Pickup, Roger W.; Wilkinson, Mark; Gatherer, Derek (American Society for Microbiology https://doi.org/10.1128/MRA.00835-18, 2018-07-12)
    ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2018. Sequence variation in multidrug-resistant plasmid pLUH01, isolated from human nasopharyngeal swabs. Microbiology resource announcements [online], 7(1), article e00835-18. Available from: https://doi.org/10.1128/MRA.00835-18
    Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 ...
  • Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. 

    Mazur-Marzec, Hanna; Fidor, Anna; Ceglowska, Marta; Wieczerzak, Ewa; Kropidlowska, Magdalena; Goua, Marie; Macaskill, Jenny; Edwards, Christine (MDPI https://doi.org/10.3390/md16070220, 2018-06-26)
    MAZUR-MARZEC, H., FIDOR, A., CEGLOWSKA, M., WIECZERZAK, E., KROPIDLOWSKA, M., GOUA, M., MACASKILL, J. and EDWARDS, C. 2018. Cyanopeptolins with trypsin and chymotrypsin inhibitory activity from the cyanobacterium nostoc edaphicum CCNP1411. Marine drugs [online], 16(7), article ID 220. Available from: https://doi.org/10.3390/md16070220
    Cyanopeptolins (CPs) are one of the most frequently occurring cyanobacterial peptides, many of which are inhibitors of serine proteases. Some CP variants are also acutely toxic to aquatic organisms, especially small ...
  • A qualitative study of the perspectives of older people in remote Scotland on accessibility to healthcare, medicines and medicines-taking. 

    Stewart, Derek C.; Gibson-Smith, Kathrine; Cunningham, Scott; Pfleger, Sharon; Rushworth, Gordon F. (Springer https://doi.org/10.1007/s11096-018-0684-y, 2018-07-09)
    STEWART, D., GIBSON-SMITH, K., CUNNINGHAM, S., PFLEGER, S and RUSHWORTH, G. 2018. A qualitative study of the perspectives of older people in remote Scotland on accessibility to healthcare, medicines and medicines-taking. International journal of clinical pharmacy [online], First Online. Available from: https://doi.org/10.1007/s11096-018-0684-y.
    Background: Recent evidence highlights the disproportionate rates of health inequality often experienced within remote and rural communities. Access to medicines within remote and rural communities may also prove problematic. ...
  • Open circuit voltage and state of charge relationship functional optimization for the working state monitoring of the aerial lithium-ion battery pack. 

    Wang, Shunli; Fernandez, Carlos; Zou, Chuan-Yun; Yu, Chun-Mei; Li, Xiao-Xia; Pei, Shi-Jie; Xie, Wei (Elsevier https://doi.org/10.1016/j.jclepro.2018.07.030, 2018-07-06)
    WANG, S.-L., FERNANDEZ, C., ZOU, C.-Y., YU, C.-M., LI, X.-X., PEI, S.-J. and XIE, W. 2018. Open circuit voltage and state of charge relationship functional optimization for the working state monitoring of the aerial lithium-ion battery pack. Journal of cleaner production [online], 198, pages 1090-1104. Available from: https://doi.org/10.1016/j.jclepro.2018.07.030
    The aerial lithium-ion battery pack works differently from the usual battery packs, the working characteristic of which is intermittent supplement charge and instantaneous large current discharge. An adaptive state of ...
  • Development of consensus based national antimicrobial stewardship competencies for UK undergraduate healthcare professional education. 

    Courtenay, Molly; Lim, Rosemary; Castro-Sanchez, Enrique; Deslandes, Rhian; Hodson, Karen; Morris, Gary; Reeves, Scott; Weiss, Marjorie; Ashiru-Oredope, Diane; Bain, Heather; Black, Adam; Bosanquet, Joanne; Cockburn, Alison; Duggan, Catherine; Fitzpatrick, Matthew; Gallagher, Rose; Grant, Daniel; McEwen, Jo; Reid, Nicholas; Sneddon, Jacqueline; Stewart, Derek C.; Tonna, Antonella P.; White, Pip (Elsevier https://doi.org/10.1016/j.jhin.2018.06.022, 2018-06-30)
    COURTENAY, M., LIM, R., CASTRO-SANCHEZ, E., DESLANDES, R., HODSON, K., MORRIS, G., REEVES, S., WEISS, M., ASHIRU-OREDOPE, D., BAIN, H., BLACK, A., BOSANQUET, J., COCKBURN, A., DUGGAN, C., FITZPATRICK, M., GALLAGHER, R., GRANT, D., MCEWEN, J., REID, N., SNEDDON, J., STEWART, D., TONNA, A. and WHITE, P. 2018. Development of consensus based national antimicrobial stewardship competencies for UK undergraduate healthcare professional education. Journal of hospital infection [online], In Press. Available from: https://doi.org/10.1016/j.jhin.2018.06.022
    Background: Healthcare professionals are involved in an array of patient and medicine related stewardship activities, for which an understanding and engagement with antimicrobial stewardship (AMS) is important. Undergraduate ...
  • The effect of administration of fenbendazole on the microbial hindgut population of the horse. 

    Crotch-Harvey, Laura; Thomas, Leigh-Anne; Worgan, Hilary J.; Douglas, Jamie-Leigh; Gilby, Diane E.; McEwan, Neil R. (Japanese Society of Equine Science https://doi.org/10.1294/jes.29.47, 2018-07-06)
    CROTCH-HARVEY, L., THOMAS, L.-A., WORGAN, H.J., DOUGLAS, J.-L., GILBY, D.E. and MCEWAN, N.R. 2018. The effect of administration of fenbendazole on the microbial hindgut population of the horse. Journal of equine science [online], 29(2), pages 47-51. Available from: https://doi.org/10.1294/jes.29.47
    Anthelmintics are used as anti-worming agents. Although known to affect their target organisms, nothing has been published regarding their effect on other digestive tract organisms, or metabolites produced by them. The ...

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