Show simple item record

dc.contributor.authorHuang, Zi
dc.contributor.authorZhou, Xiaofang
dc.contributor.authorSong, Dawei
dc.contributor.editorChen, Yi-Ping Phoebe
dc.contributor.editorWong, Limsoon
dc.date.accessioned2009-08-27T14:41:37Z
dc.date.available2009-08-27T14:41:37Z
dc.date.issued2005-01
dc.identifier.citationHUANG, Z., ZHOU, X. and SONG, D., 2005. High dimensional indexing for protein structure matching. In: Y-P. P. CHEN and L. WONG eds. Proceedings of the 3rd Asia-Pacific Bioinformatics Conference. 17-21 January 2005. Singapore: Imperial College Press. pp. 21-30.en
dc.identifier.isbn9781860944772en
dc.identifier.urihttp://hdl.handle.net/10059/408
dc.description.abstractFor determining functionality dependencies between two proteins, both represented as 3D structures, it is an essential condition that they have a matching structure. As 3D structures for proteins are large, complex and constantly evolving, it is very time-consuming to identify possible locations and sizes of such a matching structure for a given protein against a large protein database. In this paper, we introduce a novel representation model and apply a transformation and formalization to this problem. We then propose a database solution by using innovative high dimensional indexing mechanisms. Experimental results demonstrate a promising performance of the high dimensional indexing to this biologically critical but previously computationally prohibitive problem.en
dc.description.sponsorshipThe work reported in this paper has been funded in part by the Australian Research Council (Grant No. DP0344488) and the Co-operative Centre for Enterprise Distributed Systems Technology (DSTC) through the Australian Federal Government’s CRC Programme (Department of Education, Science and Training).en
dc.format.extent161710 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherImperial College Press.en
dc.relation.ispartofProceedings of the 3rd Asia Pacific Bioinformatics Conference.en
dc.rightsCopyright : Imperial College Press.en
dc.subjectProtein structuresen
dc.subjectHigh dimensional indexingen
dc.titleHigh dimensional indexing for protein structure matchingen
dc.typeConference publicationsen
dc.publisher.urihttp://ebooks.worldscinet.com/ISBN/9781860947322/9781860947322.shtmlen


Files in this item

This item appears in the following Collection(s)

Show simple item record