Now showing items 3-22 of 37

  • Biochemical adaptations in early starvation: observations on sex difference. 

    Broom, John; Fleck, A.; Davidson, D. F.; Rosenburg, C.; Durnin, J. V. G. A. (Cambridge University Press. http://dx.doi.org/10.1079/PNS19780048, 1978-12)
    BROOM, J., FLECK, A., DAVIDSON, D. F., ROSENBURG, C. and DURNIN, J. V. G. A., 1978. Biochemical adaptations in early starvation: observations on sex difference. Proceedings of the Nutrition Society, 37 (3), pp. 92A.
  • Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. 

    Barron, Gemma A.; Goua, Marie; Kuraoka, Isao; Bermano, Giovanna; Iwai, Shigenori; Kong Thoo Lin, Paul (Elsevier http://dx.doi.org/10.1016/j.cbi.2015.10.017, 2015-12-05)
    BARRON, G. A., GOUA, M., KURAOKA, I., BERMANO, G., IWAI, S. and LIN, P. K. T. L., 2015. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions, Vol 242, pp. 307-315.
    Bisnaphthalimidopropyl diaminodicyclohexylmethane (BNIPDaCHM) bisintercalates to DNA and is a potential anti-cancer therapeutic. In an attempt to elucidate the mechanism(s) underlying the potential of BNIPDaCHM; earlier ...
  • Changes in body composition after thermal injury in the rat. 

    Shamma, G. A. Al; Goll, C. C.; Baird, T. B.; Broom, John; Nicholas, G. A.; Richards, J. R. (Cambridge University Press http://dx.doi.org/10.1079/BJN19790126, 1979)
    SHAMMA, G. A. AL, GOLL. C. C., BAIRD, T. B., BROOM, J., NICHOLAS, G. A. and RICHARDS, J. R., 1979. Changes in body composition after thermal injury in the rat. British Journal of Nutrition, 42 (3), pp. 367-375.
    1. The effects on body composition, measured by direct techniques, of a controlled 25% body-surfacearea thermal injury have been studied in two groups of forty male Wistar rats. 2. The extent of weight loss in the animals ...
  • Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. 

    Barron, Gemma A.; Goua, Marie; Wahle, Klaus; Bermano, Giovanna (Spandidos Publications https://doi.org/10.3892/or.2017.5803, 2017-07-11)
    BARRON, G.A., GOUA, M., WAHLE, K.W.J. and BERMANO, G. 2017. Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. Oncology reports [online], 38(3), pages 1886-1894. Available from: https://doi.org/10.3892/or.2017.5803
    The present study exploited a versatile in vitro endothelial cell/fibroblast co-culture cell system to investigate the association between angiogenesis and breast cancer by comparing the capacity of plasma from women with ...
  • A comparison of weight loss outcomes in Black and Caucasian women following a very-low calorie diet (VLCD). 

    Rolland, Catherine; Mulholland, Yvonne; Hallam, C.; Lula, S.; Dyson, L.; Broom, Iain (Karger http://dx.doi.org/10.1159/000178128, 2012)
    ROLLAND, C., MULHOLLAND, Y., HALLAM, C., LULA, S., DYSON, L. and BROOM, I., 2012. A comparison of weight loss outcomes in Black and Caucasian women following a very-low calorie diet (VLCD). Obesity Facts, 5 (S1), p. 94
  • Defying geometric similarity: shape centralization in male UK offshore workers. 

    Stewart, Arthur D.; Ledingham, Robert J.; Furnace, Graham; Williams, Hector; Nevill, Alan M. (Wiley https://doi.org/10.1002/ajhb.22935, 2016-11-01)
    STEWART, A.D., LEDINGHAM, R.J., FURNACE, G., WILLIAMS, H. and NEVILL, A.M. 2016. Defying geometric similarity: shape centralization in male UK offshore workers. American journal of human biology [online], 29(3), e22935. Available from: https://doi.org/10.1002/ajhb.22935
    Objectives - Applying geometric similarity predictions of body dimensions to specific occupational groups has the potential to reveal useful ergonomic and health implications. This study assessed a representative sample ...
  • The effect of very-low calorie diets on renal and hepatic outcomes: a systematic review. 

    Rolland, Catherine; Mavroeidi, Alexandra; Johnston, Kelly L.; Broom, John (Dove Press. http://dx.doi.org/10.2147/DMSO.S51151, 2013-10)
    ROLLAND, C., MAVROEIDI, A., JOHNSTON, K. L. and BROOM, J., 2013. The effect of very-low calorie diets on renal and hepatic outcomes: a systematic review. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume 2013 (6), pp. 393-401.
    Very low-calorie diets (VLCDs) are an effective means by which to induce clinically significant weight loss. However, their acceptance by health care practitioners and the public is generally lower than that for other ...
  • Effect of weight loss on adipokine levels in obese patients. 

    Rolland, Catherine; Hession, Michelle; Broom, Iain (Dove Medical Press http://dx.doi.org/10.2147/DMSO.S22788, 2011-08)
    ROLLAND, C., HESSION, M. and BROOM, I., Effect of weight loss on adipokine levels in obese patients. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 4, pp. 315 – 323.
    Background: Adipose tissue functions as an endocrine organ by releasing adipokines which have important roles in the regulation of inflammation and insulin sensitivity. Although there is evidence of improvements in the ...
  • The effects of post-operative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. 

    Broom, John; Brackenridge, I. E.; Simpson, E.; Miller, J. D. B.; Morrison, I. (Cambridge University Press. http://dx.doi.org/10.1079/PNS19860042, 1986-02)
    BROOM, J., BRACKENRIDGE, I. E., SIMPSON, E., MILLER, J. D. B. and MORRISON, I., 1986. The effects of post-operative metabolic support on lipolytic rates in patients undergoing elective abdominal surgery. Proceedings of the Nutrition Society, 45 (1), 20A.
  • The effects of very-low-calorie diets on HDL: a review. 

    Rolland, Catherine; Broom, Iain (Hindawi http://dx.doi.org/10.1155/2011/306278, 2011)
    ROLLAND, C. and BROOM, I., 2011. The effects of very-low calorie diets on HDL: a review. Cholesterol, 2011, article ID 306278.
    This paper investigates the effects of very-low-calorie diets (VLCDs) used in the treatment of obesity on high-density lipoprotein (HDL) levels. Although the studies varied widely in their intervention format, duration, ...
  • Engaging patients, clinicians and health funders in weight management: the Counterweight Programme. 

    Counterweight Project Team; McQuigg, Maria; Brown, Jennifer E.; Broom, Iain; Laws, Rachel A.; Reckless, John P. D.; Noble, Paula A.; Kumar, Sudhesh; McCombie, E. Louise; Lean, Mike E. J.; Lyons, G. Felicity; Mongia, Sarika; Frost, Gary S.; Quinn, Marney F.; Barth, Julian H.; Haynes, Sarah M.; Finer, Nick; Haslam, David W.; Ross, Hazel M.; Hole, David J.; Radziwonik, Steven (Oxford University Press http://dx.doi.org/10.1093/fampra/cmn081, 2008-12)
    THE COUNTERWEIGHT PROJECT TEAM: MCQUIGG, M., BROWN, J. E., BROOM, J. I., LAWS, R. A., RECKLESS, J. P. D., NOBLE, P. A., KUMAR, S., MCCOMBIE, E. L., LEAN, M. E. J., LYONS, G. F., MONGIA, S., FROST, G. S., QUINN, M. F., BARTH, J. H., HAYNES, S. M., FINER, N., HASLAM, D. W., ROSS, H. M., HOLE, D. J., and RADZIWONIK, S., 3008. Engaging patients, clinicians and health funders in weight management: the Counterweight Programme. Family Practice, 25 (S1), pp. i79-i86.
    Background. The Counterweight Programme provides an evidence based and effective approach for weight management in routine primary care. Uptake of the programme has been variable for practices and patients. Aim. To explore ...
  • Global warming: is weight loss a solution? 

    Gryka, Anna; Broom, John; Rolland, Catherine (Nature Publishing Group http://dx.doi.org/10.1038/ijo.2011.151, 2012-03)
    GRYKA, A., BROOM, J, and ROLLAND, C., 2012. Global warming: is weight loss a solution? International Journal of Obesity, 36 (3), pp. 474-476.
    The current climate change has been most likely caused by the increased greenhouse gas emissions. We have looked at the major greenhouse gas, carbon dioxide (CO2), and estimated the reduction in the CO2 emissions that would ...
  • The implementation of the Counterweight Programme in Scotland, UK. 

    Counterweight Project Team; Bell-Higgs, Anna E.; Brosnahan, Naomi T.; Clarke, Anne M.; Dow, Maria S. A.; Haynes, Sarah M.; Lyons, G. Felicity; McCombie, E. Louise; Mongia, Sarika; Noble, Paula A.; Quinn, Marney F.; Regan, Paula J.; Ross, Hazel M.; Thompson, Frances E.; Vermeulen, Adri; Broom, Iain; Reckless, John P. D.; Kumar, Sudhesh; Lean, Michael E. J.; Frost, Gary S.; Finer, Nick; Haslam, David W.; Morrison, David; Sloan, Billy; McLoone, Philip (Oxford University Press. http://dx.doi.org/10.1093/fampra/cmr074, 2012-04)
    COUNTERWEIGHT PROJECT TEAM, 2012. The implementation of the Counterweight Programme in Scotland, UK. Family Practice, 29 (Supp. 1), pp. i139-i144.
    Background. The Counterweight Programme is a proven model for the management of obesity in the UK, evaluated over 5 years (2000–05) and demonstrating clinical and cost effectiveness. The Scottish Government commissioned ...
  • Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. 

    Weichhaus, Michael; Broom, John; Wahle, Klaus; Bermano, Giovanna (Spandidos Publications. http://dx.doi.org/10.3892/ol.2014.2085, 2014-07)
    WEICHHAUS, M., BROOM, J., WAHLE, K. and BERMANO, G., 2014. Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling. Oncology Letters, 8 (1), pp. 374-378.
    Leptin is a hormone secreted by white fat tissue and signals the amount of overall body fat to the hypothalamus. The circulating concentration of leptin correlates with the level of obesity. Breast cancer risk is higher ...
  • Long-term weight loss maintenance and management following a VLCD: a 3-year outcome. 

    Rolland, Catherine; Johnston, Kelly L.; Lula, Sadiq; Macdonald, Ian; Broom, Iain (Wiley http://dx.doi.org/10.1111/ijcp.12300, 2014-03)
    ROLLAND, C., JOHNSTON, K. L., LULA, S., MACDONALD, I. and BROOM, I., 2014. Long-term weight loss maintenance and management following a VLCD: a 3-year outcome. International Journal of Clinical Practice, 68 (3), pp. 379-387.
    Background: Effective weight loss treatment is important as obesity has severe health and socioeconomic repercussions. Emerging evidence suggests that rapid initial weight loss results in better long-term weight loss ...
  • Low-carbohydrate diets, obesity and type 2 diabetes: a review. 

    Gryka, Anna; Broom, Iain; Rolland, Catherine (Teknoscienze Srl http://agro-food-industry.teknoscienze.com/testata.asp?id_testata=257&folder=supplements, 2012-03)
    GRYKA, A., BROOM, I. and ROLLAND, C., 2012. Low-carbohydrate diets, obesity and type 2 diabetes: a review. Agro Food Hi-Tech Industry: Weight Management Supplement, 23 (2) Supp. Pp. 12-14.
    This review examines the effects of low-carbohydrate, high-protein diets (LCHO) (<150g carbohydrate/d) on glycaemia and cardiovascular risk, energy expenditure, appetite and satiety, liver and kidney function, bone metabolism, ...
  • Obesity and its health impact in Africa: a systematic review. 

    Adeboye, Bridget; Bermano, Giovanna; Rolland, Catherine (Clinics Cardive Publishing. http://dx.doi.org/10.5830/CVJA-2012-040, 2012-10)
    ADEBOYE, B., BERMANO, G. and ROLLAND, C., 2012. Obesity and its health impact in Africa: a systematic review. Cardiovascular Journal of Africa, 23 (9), pp. 512-521.
    Obesity and its association with co-morbidities in Africa are on the rise. This systematic review examines evidence of obesity and its association with co-morbidities within the African continent. Comparative studies ...
  • Optimizing acceptability and feasibility of an evidence-based behavioral intervention for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: an open-pilot intervention study in secondary care. 

    Dombrowski, Stephan U.; Sniehotta, Falko F.; Johnston, Marie; Broom, Iain; Kulkarni, Utkarsh; Brown, Jennifer E.; Murray, Lynne; Soares, Vera A. (Elsevier. http://dx.doi.org/10.1016/j.pec.2011.08.003, 2012-04)
    DOMBROWSKI, S. U., SNIEHOTTA, F. F., JOHNSTON, M., BROOM, I., KULKARNI, U., BROWN, J., MURRAY, L., SOARES, V. A., 2012. Optimizing acceptability and feasibility of an evidence-based behavioral intervention for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: an open-pilot intervention study in secondary care. Patient Education and Counseling, 87 (1), pp. 108-119.
    Objective To test and optimize the feasibility and acceptability of a physical activity (PA) and healthy eating behavior change intervention for obese adults with obesity-related co-morbidities or additional risk factors ...
  • Over-the-counter Orlistat: early experiences, views and attitudes of community pharmacists in Great Britain. 

    Weidmann, Anita Elaine; Cunningham, Scott; Gray, Gwen; Hansford, Denise; McLay, James S.; Broom, John; Stewart, Derek C. (Springer Verlag http://dx.doi.org/10.1007/s11096-011-9516-z, 2011-08)
    WEIDMAN, A. E., CUNNINGHAM, S., GRAY, G., HANSFORD, D., MCLAY, J., BROOM, J. and STEWART, D., 2011. Over-the-counter Orlistat: early experiences, views and attitudes of community pharmacists in Great Britain. International Journal of Clinical Pharmacy, 33 (4), pp. 627-633.
    Objectives of the study To describe community pharmacists’ early experiences, views and attitudes with over-the-counter orlistat, 9 months post legal re-classification from November 2009 to January 2010. Setting 13,200 ...
  • Protein synthesis in the rat liver after fracture of the femur. 

    Khan, S. N.; Tilstone, W. J.; Fleck, A.; Broom, Iain (Cambridge University Press. http://dx.doi.org/10.1079/PNS19740058, 1974-12)
    KHAN, S. N., TILSTONE, W. J., FLECK, A. and BROOM, I., 1974. Protein synthesis in the rat liver after fracture of the femur. Proceedings of the Nutrition Society, 33 (3), 93A