OpenAIR @ RGU >
Health and Social Care >
Centre for Obesity Research and Epidemiology >
Journal articles (Centre for Obesity Research and Epidemiology) >

Please use this identifier to cite or link to this item:
This item has been viewed 4 times in the last year. View Statistics

Files in This Item:

File Description SizeFormat
Rolland BJN 108 5 very-low-energy.pdf2.09 MBAdobe PDFView/Open
Title: Very-low-energy diets and morbidity: a systematic review of longer-term evidence.
Authors: Mulholland, Yvonne
Nicokavoura, Efsevia
Broom, John
Rolland, Catherine
Keywords: Obesity
Systematic reviews
Very-low-energy diets
Issue Date: Sep-2012
Publisher: Cambridge University Press
Citation: MULHOLLAND, Y., NICOKAVOURA, E., BROOM, J. and ROLLAND, C., 2012. Very-low-energy diets and morbidity: a systematic review of longer-term evidence. British Journal of Nutrition, 108 (5), pp. 832-851.
Abstract: Evidence from the literature supports the safe use of very-low-energy diets (VLED) for up to 3 months in supervised conditions for patients who fail to meet a target weight loss using a standard low-fat, reduced-energy approach. There is, however, a need for longer-term outcomes on obesity and associated morbidities following a VLED. The present systematic review aims to investigate longer-term outcomes from studies using VLED, with a minimum duration of 12 months, published between January 2000 and December 2010. Studies conducted in both children and adults, with a mean/median BMI of ≥ 28 kg/m2 were included. PubMed, MEDLINE, Web of Science and Science Direct were searched. Reference lists of studies and reviews were manually searched. Weight loss or prevention of weight gain and morbidities were the main outcomes assessed. A total of thirty-two out of 894 articles met the inclusion criteria. The duration of the studies ranged from 12 months to 5 years. Periods of VLED ranged from 25 d to 9 months. Several studies incorporated aspects of behaviour therapy, exercise, low-fat diets, low-carbohydrate diets or medication. Current evidence demonstrates significant weight loss and improvements in blood pressure, waist circumference and lipid profile in the longer term following a VLED. Interpretation of the results, however, was restricted and conclusions with which to guide best practice are limited due to heterogeneity between the studies. The present review clearly identifies the need for more evidence and standardised studies to assess the longer-term benefits from weight loss achieved using VLED.
ISSN: 0007-1145
Appears in Collections:Journal articles (Centre for Obesity Research and Epidemiology)

All items in OpenAIR are protected by copyright, with all rights reserved.


   Disclaimer | Freedom of Information | Privacy Statement |Copyright ©2012 Robert Gordon University, Garthdee House, Garthdee Road, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781