Weight loss for individuals with type 2 diabetes following a very-low-calorie diet in a community-based setting with trained facilitators for 12 weeks.
Johnston, Kelly L.
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ROLLAND, C., LULA, S., JENNER, C., DYSON, L., MACDONALD, I., JOHNSTON, K. L. and BROOM, I., 2013. Weight loss for individuals with type 2 diabetes following a very-low-calorie diet in a community-based setting with trained facilitators for 12 weeks. Clinical Obesity, 3 (5), pp. 150-157.
Approximately 80% of people with type 2 diabetes mellitus (T2DM) are overweight or obese, and obesity compounds the cardiovascular risk of T2DM. The aim of this retrospective study was twofold: first to investigate whether a 12 week, community based VLCD programme can result in important weight loss; and second to investigate any potential difference in the weight loss achieved using this community based approach in individuals with and without T2DM. Three hundred and fifty five participants with T2DM were matched for age, BMI and gender to participants without T2DM (Total cohort comprised 204 males: 506 females; (mean ± standard deviation) age (years) 54.0 ± 9.1; BMI (kg/m2) 41.6 ± 8.1; weight (kg) 116.1 ± 25.1). The programme included a daily intake of 550kcal in addition to group support and behaviour therapy provided by trained facilitators within a community-based setting. After 12 weeks, there was significant weight loss within each group when compared to baseline (T2DM: 115.0 ± 24.4 kg vs 96.7 ± 21.4 kg, p <0.0001; non-T2DM: 117.2 ± 25.8 kg vs 97.3 ± 22.2 kg, p < 0.0001). At 12 weeks, weight change (-18.3 ± 7.3 kg vs -19.9 ± 7.0 kg, p = 0.012) and BMI change (-6.7 ± 2.9 kg/m2 vs -7.1 ± 2.1 kg/m2, p = 0.011) were significantly less in the T2DM group when compared to the non-T2DM group. Our results suggest that the use of VLCD approaches for weight management in T2DM can achieve more than 90% of the weight loss seen in obese individuals without T2DM.